Evidence map›Paper›PMID 32047895›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2020

Consistent Detection of 2019 Novel Coronavirus in Saliva.

Kelvin Kai-Wang To, Owen Tak-Yin Tsang, Cyril Chik-Yan Yip, Kwok-Hung Chan, Tak-Chiu Wu, Jacky Man-Chun Chan, Wai-Shing Leung, Thomas Shiu-Hong Chik, Chris Yau-Chung Choi, Darshana H Kandamby and 8 more

8 registry-linked trialsOpen access · bronzeAbstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 8 registered trials, which are not on this map. Cited by 881 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
881citing papers in PubMed, 5 pooled it
47.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04578509 completednot on this map

Evaluation of a Screening Program for SARS-CoV-2 Infection in the General Population Based on the Use of New Detection Approaches or for Diagnostic Orientation on Saliva (COVID-19)

TypeobservationalSponsorAssistance Publique - Hôpitaux de ParisRan2020 to 2021Enrolled5,197ConditionsSARS-CoV-2 Infection, COVID-19ArmsNasopharyngeal swab, Saliva sample, axillary sweat sample, Data collection
NCT04581889 completednot on this map

Prospective, Seroepidemiological, Non-invasive Cohort Study in Tübingen Children Age-stratified by Nursery and School Attendance

TypeobservationalSponsorUniversity Hospital TuebingenRan2020 to 2022Enrolled2,380ConditionsSevere Acute Respiratory SyndromeArmsDiagnostic test
NCT04603794 phase4unknown statusnot on this map

Comparison of Normal Saline, Hydrogen Peroxide, Chlorhexidine and Povidone-Iodine Mouth Rinses in COVID-19 Patients

TypeinterventionalSponsorOhio State UniversityRan2020 to 2020Enrolled60ConditionsCOVID-19Arms0.5% Povidone Iodine, 0.12% Chlorhexidine Gluconate Mouth Rinse, 1% Hydrogen Peroxide, 0.9% Normal Saline
NCT04609774 completednot on this map

Aerosol Transmission of Severe Acute Respiratory Syndrome Coronavirus: a Dilemma

TypeobservationalSponsorHospital Italiano de Buenos AiresRan2020 to 2020Enrolled8ConditionsCoronavirus Disease (COVID-19)ArmsSevere Acute Respiratory Syndrome CoronaVirus 2 detection
NCT04721457 phase4completednot on this mapstarted 2021, after this paper: background citation

Mouth Rinses Efficacy on Salivary SARS-CoV-2 Viral Load: A Randomized Clinical Trial

TypeinterventionalSponsorKing Abdulaziz UniversityRan2021 to 2021Enrolled90ConditionsSARS-CoV-2, COVID-19, Mouthwashes, Viral LoadArmsDistilled Water, 1% Povidone Iodine (PVP-I), 1.5% Hydrogen Peroxide (H2O2), 0.075% Cetylpyridinium Chloride (CPC), 0.1% Sodium Hypochlorite
NCT04723446 nacompletednot on this mapstarted 2021, after this paper: background citation

Efficacy of Three Antimicrobial Mouthwashes in Reducing SARS-CoV-2 Viral Load in the Saliva of Patients Diagnosed With COVID-19: A Pilot Study

TypeinterventionalSponsorQueen Mary University of LondonRan2021 to 2021Enrolled54ConditionsCovid19, CoronavirusArmsCorsodyl® Alcohol free -0.2 % Chlorhexidine digluconate, Colgate Peroxyl® -1.5% Hydrogen peroxide, Oral-B® Gum & Enamel Care -Cetylpyridinium chloride, No rinsing
NCT04894409 nacompletednot on this map

Evaluation of Silver Nanoparticles as an Oropharyngeal Product (Mouthwash) and Nasal Hygiene, by Health Personnel Working at the Tijuana General Hospital Exposed to Patients Diagnosed With Atypical Pneumonia Caused by SARS-CoV-2

TypeinterventionalSponsorCluster de Bioeconomia de Baja California, A.CRan2020 to 2020Enrolled231ConditionsCoronavirus Disease 2019 (COVID-19)ArmsMouthwash and nose rinse with the AgNPs solution, Mouthwashes and nose rinse in a conventional way
NCT06272019 nacompletednot on this mapstarted 2023, after this paper: background citation

Alternative Application Methods of Pre-procedural Povidone Iodine Mouthrinse

TypeinterventionalSponsorChulalongkorn UniversityRan2023 to 2024Enrolled25ConditionsThe Retention of Iodine in Saliva Over the Time, The Comparison of Iodine in Saliva Between Gargle and SwabArmsIodine gargle
3 · Its place in the literature

Who cites it

881 citing papers in PubMed, 5 syntheses or guidelines pooled it, 1,990 citations in OpenAlex.

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821 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 2 countries.

Kelvin Kai-Wang ToState Key Laboratory for Emerging Infectious Diseases, Department of Microbiology, Carol Yu Centre for Infection, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China.
Owen Tak-Yin TsangDepartment of Medicine and Geriatrics, Princess Margaret Hospital, Hong Kong Special Administrative Region, China.
Cyril Chik-Yan YipState Key Laboratory for Emerging Infectious Diseases, Department of Microbiology, Carol Yu Centre for Infection, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China.
Kwok-Hung ChanState Key Laboratory for Emerging Infectious Diseases, Department of Microbiology, Carol Yu Centre for Infection, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China.
Tak-Chiu WuDepartment of Medicine, Queen Elizabeth Hospital, Hong Kong Special Administrative Region, China.
Jacky Man-Chun ChanDepartment of Medicine and Geriatrics, Princess Margaret Hospital, Hong Kong Special Administrative Region, China.
Wai-Shing LeungDepartment of Medicine and Geriatrics, Princess Margaret Hospital, Hong Kong Special Administrative Region, China.
Thomas Shiu-Hong ChikDepartment of Medicine and Geriatrics, Princess Margaret Hospital, Hong Kong Special Administrative Region, China.
Chris Yau-Chung ChoiDepartment of Medicine and Geriatrics, Princess Margaret Hospital, Hong Kong Special Administrative Region, China.
Darshana H KandambyIntensive Care Unit, Princess Margaret Hospital, Hong Kong Special Administrative Region, China.
David Christopher LungDepartment of Pathology, Queen Elizabeth Hospital, Hong Kong Special Administrative Region, China.
Anthony Raymond TamDepartment of Medicine, Queen Mary Hospital, Hong Kong Special Administrative Region, China.
Rosana Wing-Shan PoonState Key Laboratory for Emerging Infectious Diseases, Department of Microbiology, Carol Yu Centre for Infection, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China.
Agnes Yim-Fong FungState Key Laboratory for Emerging Infectious Diseases, Department of Microbiology, Carol Yu Centre for Infection, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China.
Ivan Fan-Ngai HungDepartment of Medicine, Queen Mary Hospital, Hong Kong Special Administrative Region, China.
Vincent Chi-Chung ChengState Key Laboratory for Emerging Infectious Diseases, Department of Microbiology, Carol Yu Centre for Infection, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China.
Jasper Fuk-Woo ChanState Key Laboratory for Emerging Infectious Diseases, Department of Microbiology, Carol Yu Centre for Infection, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China.
Kwok-Yung YuenState Key Laboratory for Emerging Infectious Diseases, Department of Microbiology, Carol Yu Centre for Infection, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China.
University of Hong Kong · HKQueen Mary Hospital · CNQueen Elizabeth Hospital · CNUniversity of Hong Kong - Shenzhen Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The 2019 novel coronavirus (2019-nCoV) was detected in the self-collected saliva of 91.7% (11/12) of patients. Serial saliva viral load monitoring generally showed a declining trend. Live virus was detected in saliva by viral culture. Saliva is a promising noninvasive specimen for diagnosis, monitoring, and infection control in patients with 2019-nCoV infection.

Indexed as

AdultAgedAnimalsBetacoronavirusCell LineChlorocebus aethiopsCoronavirus InfectionsCOVID-19FemaleHong KongHumansInfection ControlMaleMiddle AgedPandemicsPneumonia, Viral2019 novel coronavirusCOVID-19diagnosticssalivatransmissionviral load

Identifiers

PMID32047895
PMCPMC7108139
OpenAlexW3005690553

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

and 2 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.