ArticleWellcome open research2019
Management of intracranial tuberculous mass lesions: how long should we treat for?
Article in Wellcome open research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- Cerebral tuberculoma in pregnancy (Jan 1975-May 2025): a systematic review and descriptive analysis of 33 published cases.BMC infectious diseases · 2026Pooled it
- A clinical practice guideline for tuberculous meningitis.The Lancet. Infectious diseases · 2026Guideline
- Right Temporal Lobe Tuberculoma Presenting as Seizures in a Patient With Pulmonary Tuberculosis.The American journal of case reports · 2026Article
- Extra-axial tuberculoma mimicking brain tumor on MRI: A rare case in an immunocompetent adult.Radiology case reports · 2026Article
- Thalamic Tuberculoma Presenting as Isolated Gait Disturbance Without Systemic or Meningeal Symptoms in a 2-Year-Old Child: A Case Report.International medical case reports journal · 2026Article
- Frontal Tuberculoma Presenting With Atypical Foster Kennedy Syndrome in a Pregnant Patient.Clinical case reports · 2025Article
- Large Tuberculous Mass Lesions Involving the Brain: Outcomes and Management.The American journal of tropical medicine and hygiene · 2025Observational
- Mortality predictors and diagnostic challenges in adult tuberculous meningitis: a retrospective cohort of 100 patients.Tropical medicine and health · 2025Article
- Paradoxical Reactions of Central Nervous System Tuberculosis: Report of Three Immunocompetent Cases.Case reports in infectious diseases · 2025Article
- Imaging panorama of pediatric central nervous system tuberculosis.Pediatric radiology · 2024Review
- Posterior fossa tuberculosis: Unusual presentations of a common disease and literature review.World neurosurgery: X · 2024Article
- A Case of Multiple Brain Tuberculomas in the Subarachnoid Cisterns: Recognition of Radiological Characteristics Regarding the Development of Paradoxical Response during Antituberculosis Treatment.NMC case report journal · 2024Article
- Review
- Which trial do we need? A global, adaptive, platform trial to reduce death and disability from tuberculous meningitis.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2023Article
- Intracranial Tuberculoma in a Pregnant Lady: A Hitherto Unknown Case and a Successful Outcome.Cureus · 2022Article
- Granulomatous Diseases of the Central Nervous System.Current neurology and neuroscience reports · 2022Review
- Case report: Depressive disorder with peripartum onset camouflages suspected intracranial tuberculoma.Frontiers in psychiatry · 2022Article
- Rare manifestation of common disease: An adolescent girl with transient ischemic attack (TIA) like presentation in multiple tuberculoma.Journal of family medicine and primary care · 2021Article
- CSF Metabolomics of Tuberculous Meningitis: A Review.Metabolites · 2021Review
- Central nervous system tuberculosis.Current opinion in neurology · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 6 institutions in 4 countries.
Funding
Abstract
Tuberculous intracranial mass lesions are common in settings with high tuberculosis (TB) incidence and HIV prevalence. The diagnosis of such lesions, which include tuberculoma and tuberculous abscesses, is often presumptive and based on radiological features, supportive evidence of TB elsewhere and response to TB treatment. However, the treatment response is unpredictable, with lesions frequently enlarging paradoxically or persisting for many years despite appropriate TB treatment and corticosteroid therapy. Most international guidelines recommend a 9-12 month course of TB treatment for central nervous system TB when the infecting
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.