Evidence map›Paper›PMID 32047838›Full record

ArticleNPJ microgravity2020

Spaceflight and simulated microgravity conditions increase virulence of

Rachel Gilbert, Medaya Torres, Rachel Clemens, Shannon Hateley, Ravikumar Hosamani, William Wade, Sharmila Bhattacharya

Open access · goldAbstract read
In one paragraph

Article in NPJ microgravity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.

  1. Pooled it
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  11. Response ofJournal of bacteriology · 2024
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  13. iScience · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Rachel GilbertNASA Postdoctoral Program, Universities Space Research Association, NASA Ames Research Center, Moffett Field, CA USA.ORCID 0000-0002-1380-8012
Medaya Torres2FILMSS/Bionetics, NASA Ames Research Center, Moffett Field, CA USA.
Rachel Clemens2FILMSS/Bionetics, NASA Ames Research Center, Moffett Field, CA USA.
Shannon Hateley3Department of Molecular and Cell Biology, University of California, Berkeley, CA USA.
Ravikumar HosamaniNASA Postdoctoral Program, Universities Space Research Association, NASA Ames Research Center, Moffett Field, CA USA.
William Wade2FILMSS/Bionetics, NASA Ames Research Center, Moffett Field, CA USA.
Sharmila Bhattacharya4NASA Ames Research Center, Moffett Field, CA USA.
Ames Research Center · USUniversity of California, Berkeley · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

While it has been shown that astronauts suffer immune disorders after spaceflight, the underlying causes are still poorly understood and there are many variables to consider when investigating the immune system in a complex environment. Additionally, there is growing evidence that suggests that not only is the immune system being altered, but the pathogens that infect the host are significantly influenced by spaceflight and ground-based spaceflight conditions. In this study, we demonstrate that

Indexed as

InfectionInnate immunityMicrobiology

Identifiers

PMID32047838
PMCPMC7000411
OpenAlexW3004983543

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.