Evidence map›Paper›PMID 32047833›Full record

ArticleOpen forum infectious diseases2020

Multiple NDM-5-Expressing

Tim Flerlage, Jessica N Brazelton de Cardenas, Cherilyn D Garner, Nur A Hasan, Hiren Karathia, Amr Qudeimat, Gabriela Maron, Randall Hayden

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.9field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Evidence of transmission and dissemination of diverseApplied and environmental microbiology · 2025
    Article
  5. Emergence and Polyclonal Dissemination of blaEmerging infectious diseases · 2025
    Article
  6. Molecular and genetic features of a blaAnnals of clinical microbiology and antimicrobials · 2025
    Article
  7. Genome assembly ofFrontiers in microbiology · 2025
    Article
  8. Review
  9. High Frequency of Antibiotic Resistance Genes (ARGs) in the Lerma River Basin, Mexico.International journal of environmental research and public health · 2022
    Article
  10. Article
  11. First identification ofJournal of medical microbiology · 2022
    Article
  12. Review
  13. Emergence of a High-RiskFrontiers in microbiology · 2022
    Article
  14. Co-Occurrence of NDM-5 and RmtB in a Clinical Isolate ofFrontiers in cellular and infection microbiology · 2021
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Tim FlerlageDivision of Pediatric Critical Care Medicine, Department of Pediatrics, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Jessica N Brazelton de CardenasDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Cherilyn D GarnerDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Nur A HasanCosmosID Incorporated, Rockville, Maryland, USA.
Hiren KarathiaCosmosID Incorporated, Rockville, Maryland, USA.
Amr QudeimatDepartment of Bone Marrow Transplant and Cellular Therapy, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Gabriela MaronDepartment of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Randall HaydenDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
St. Jude Children's Research Hospital · USCosmos Corporation (United States) · USUniversity of Tennessee Health Science Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGenes conferring carbapenem resistance have disseminated worldwide among Gram-negative bacteria. Here we present longitudinal changes in clinically obtained

methodsThirty-three isolates obtained over 7 months from 1 patient were included. Clinical data were abstracted from the medical record. For each isolate, studies included phenotypic antibacterial resistance patterns, sequence typing, bacterial isolate sequencing, plasmid identification, and antibiotic resistance gene identification.

resultsSites of isolation included blood, wound culture, and culture for surveillance purposes from the perianal area. Isolates were of 5 sequence types (STs). All were resistant to multiple classes of antibiotics; 23 (69.6%) were phenotypically resistant to all carbapenems. The blaNDM-5 gene was identified in 22 (67%) isolates, all of ST-167 and ST-940, and appeared to coincide with the presence of the IncFII and IncX3 plasmid.

conclusionsWe present unique microbiologic data from 33 multidrug-resistant

Indexed as

immunocompromisedmultidrug-resistantNDM-5pediatric

Identifiers

PMID32047833
PMCPMC7003983
OpenAlexW2998806730

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.