Evidence map›Paper›PMID 32047809›Full record

ArticleBioMed research international2020

Recombinant

Mey-Fann Lee, Chu-Hui Chiang, Shyh-Jye Lin, Pei-Pong Song, Hsin-Chun Liu, Tsu-Juey Wu, Wei-Wen Lin

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. The Anti-Inflammatory Effect ofInternational journal of molecular sciences · 2024
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Ganoderma immunomodulatory proteins: mushrooming functional FIPs.Applied microbiology and biotechnology · 2022
    Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Mey-Fann LeeDepartment of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.
Chu-Hui ChiangDepartment of Plant Medicine, National Pingtung University of Science and Technology, Pingtung, Taiwan.
Shyh-Jye LinSchool of Medical Laboratory and Biotechnology, Chung Shan Medical University, Taichung, Taiwan.
Pei-Pong SongDepartment of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.
Hsin-Chun LiuDepartment of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.
Tsu-Juey WuCardiovascular Center, Taichung Veterans General Hospital, Taichung, Taiwan.
Wei-Wen LinCardiovascular Center, Taichung Veterans General Hospital, Taichung, Taiwan.ORCID https://orcid.org/0000-0002-9384-1970
Taichung Veterans General Hospital · TWChung Shan Medical University · TWNational Pingtung University of Science and Technology · TWNational Yang Ming Chiao Tung University · TWTunghai University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atherosclerosis is an inflammatory disease characterized by lipid deposits in the subendothelial space leading to severe inflammation. Nonalcoholic fatty liver disease (NAFLD) shares several risk factors with atherosclerosis, including dyslipidemia, type 2 diabetes mellitus, and metabolic syndrome, all of which lead to lipid deposition in the liver causing inflammation and fibrosis. Several clinical trials have shown that certain Chinese herbal medicines with anti-inflammatory effects can be used as adjuvant therapy to prevent the development of cardiovascular events and liver disease. Ling Zhi 8 (LZ8) is an immunomodulatory protein isolated from a medicinal mushroom and has been well documented to possess a broad range of pharmacological properties. This study aimed to evaluate the protective effects of recombinant

Indexed as

Administration, OralAnimalsAnti-Inflammatory AgentsAortaAtherosclerosisCholesterolDisease Models, AnimalDrugs, Chinese HerbalFungal ProteinsImmunomodulationLactococcus lactisLipidsLiverNon-alcoholic Fatty Liver DiseaseRabbitsRecombinant ProteinsAnti-Inflammatory AgentsCholesterolDrugs, Chinese HerbalFungal ProteinsLipidsLZ-8 protein, Ganoderma lucidumRecombinant Proteins

Identifiers

PMID32047809
PMCPMC7007749
OpenAlexW3002380018

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.