Evidence map›Paper›PMID 32047808›Full record

ArticleBioMed research international2020

Identification of Urinary Biomarkers for Exercise-Induced Immunosuppression by iTRAQ Proteomics.

Guoqin Xu, Wentao Lin, Andrew J McAinch, Xu Yan, Xiquan Weng

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05419531 (Measuring the Incidence of Colorectal Cancer in Young Endurance Athletes), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05419531 completednot on this mapstarted 2022, after this paper: background citation

Measuring the Incidence of Colorectal Cancer in Young Endurance Athletes

TypeobservationalSponsorInova Health Care ServicesRan2022 to 2025Enrolled94ConditionsColorectal CancerArmsprospective observational study - screening and follow up colonoscopy
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Review
  5. Urinary Proteomics of Simulated Firefighting Tasks and Its Relation to Fitness Parameters.International journal of environmental research and public health · 2021
    Article
  6. Urinary Biomarkers: Diagnostic Tools for Monitoring Athletes' Health Status.International journal of environmental research and public health · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Guoqin XuDepartment of Sports and Health, Guangzhou Sport University, Guangzhou 510500, China.ORCID https://orcid.org/0000-0003-1858-6997
Wentao LinDepartment of Sports and Health, Guangzhou Sport University, Guangzhou 510500, China.
Andrew J McAinchInstitute for Health and Sport, Victoria University, Melbourne 8001, Australia.
Xu YanInstitute for Health and Sport, Victoria University, Melbourne 8001, Australia.
Xiquan WengDepartment of Sports and Health, Guangzhou Sport University, Guangzhou 510500, China.ORCID https://orcid.org/0000-0001-9691-8374
Guangzhou Sport University · CNAustralian Institute for Musculoskeletal Science · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo identify noninvasive immune biomarkers of exercise-induced immunosuppression using the iTRAQ proteomics technique.

methodsFifteen healthy males were recruited and subjected to a four-week incremental treadmill running training program. After each week of training, WBC counts and CD4

resultsOur data showed that the WBC counts, CD4

conclusionFour weeks of incremental treadmill running induced immunosuppression in healthy males. By using iTRAQ proteomics, four proteins in the urine, SEMG-1, PIP, PDGFRL, and NDPK, were found to increase incrementally with the increased exercise intensity, which have the potential to be used as noninvasive immune biomarkers of exercise-induced immunosuppression.

Indexed as

BiomarkersComputational BiologyDown-RegulationExerciseExercise TestHumansImmunosuppression TherapyLymphocyte CountLymphocytesMaleMembrane Transport ProteinsNucleoside-Diphosphate KinaseProteomicsReceptors, Platelet-Derived Growth FactorRunningSeminal Vesicle Secretory ProteinsBiomarkersMembrane Transport ProteinsNucleoside-Diphosphate KinasePDGFRL protein, humanPIP protein, humanReceptors, Platelet-Derived Growth FactorSeminal Vesicle Secretory Proteinsseminal vesicle-specific antigenTumor Suppressor Proteins

Identifiers

PMID32047808
PMCPMC7003279
OpenAlexW3000889276

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.