ArticleFrontiers in medicine2019
Effects of an In-home Multicomponent Exergame Training on Physical Functions, Cognition, and Brain Volume of Older Adults: A Randomized Controlled Trial.
Article in Frontiers in medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05751551 (Feasibility and Effectiveness of a Personalized, Home-based Motor-cognitive Training Program in Community-dwelling Older Adults - a Pragmatic Pilot Randomized Controlled Trial), which is not on this map. Cited by 62 papers, 16 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Feasibility and Effectiveness of a Personalized, Home-based Motor-cognitive Training Program in Community-dwelling Older Adults - a Pragmatic Pilot Randomized Controlled Trial
Who cites it
62 citing papers in PubMed, 16 syntheses or guidelines pooled it, 128 citations in OpenAlex.
- Digital Physical Exercise Interventions for Cognitive Functions in Older Adults: Systematic Review and Bayesian Network Meta-Analysis of Randomized Controlled Trials.Journal of medical Internet research · 2026Pooled it
- Optimal type and dose of exercise for improving executive functions in older adults: a systematic review and Bayesian model-based network meta-analysis of RCTs.BMC geriatrics · 2026Pooled it
- The effectiveness of unsupervised home-based exercise for improving lower extremity physical function in older adults in Western and Eastern cultures: a systematic review and meta-analysis.BMC geriatrics · 2024Pooled it
- Multidomain interventions for sarcopenia and cognitive flexibility in older adults for promoting healthy aging: a systematic review and meta-analysis of randomized controlled trials.Aging clinical and experimental research · 2024Pooled it
- Neural Correlates of Balance Skill Learning in Young and Older Individuals: A Systematic Review and Meta-analysis.Sports medicine - open · 2024Pooled it
- Alexa, let's train now! - A systematic review and classification approach to digital and home-based physical training interventions aiming to support healthy cognitive aging.Journal of sport and health science · 2024Pooled it
- Active video games for improving health-related physical fitness in older adults: a systematic review and meta-analysis.Frontiers in public health · 2024Pooled it
- Exergames improve cognitive function in older adults and their possible mechanisms: A systematic review.Journal of global health · 2023Pooled it
- Effects of Tai Chi and Qigong on cognitive and physical functions in older adults: systematic review, meta-analysis, and meta-regression of randomized clinical trials.BMC geriatrics · 2023Pooled it
- The Effects of ICT-Based Interventions on Physical Mobility of Older Adults: A Systematic Literature Review and Meta-Analysis.International journal of clinical practice · 2023Pooled it
- Pooled it
- Self-care interventions of community-dwelling older adults: a systematic review and meta-analysis.Frontiers in public health · 2023Pooled it
- Effects of exergaming on executive function of older adults: a systematic review and meta-analysis.PeerJ · 2022Pooled it
- The Effects of Combined Cognitive-Physical Interventions on Cognitive Functioning in Healthy Older Adults: A Systematic Review and Multilevel Meta-Analysis.Frontiers in human neuroscience · 2022Pooled it
- The role of motivation factors in exergame interventions for fall prevention in older adults: A systematic review and meta-analysis.Frontiers in neurology · 2022Pooled it
- Home-Based Indoor Physical Activity Programs for Community-Dwelling Older Adults: A Systematic Review.Sports healthPooled it
- Effects of Exergame Training on Executive Function and Heart Rate Variability in Middle-Aged and Older Adults: A Randomized Controlled Study.European journal of sport science · 2025Trial
- A Newly Developed Exergame-Based Telerehabilitation System for Older Adults: Usability and Technology Acceptance Study.JMIR human factors · 2023Trial
- The Effects of Dance-Based Exergaming on Mental Rotation, General Motor Coordination, and Math Achievement in Adolescent Students: Nonrandomized Controlled Pilot Study.JMIR serious games · 2026Article
- Optimal type and dose of exercise to improve cognitive function in healthy and pre-sarcopenic older adults: a bayesian network meta-analysis of randomized controlled trials.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2026Review
2 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aging is associated with a decline in physical functions, cognition and brain structure. Considering that human life is based on an inseparable physical-cognitive interplay, combined physical-cognitive training through exergames is a promising approach to counteract age-related impairments. The aim of this study was to assess the effects of an in-home multicomponent exergame training on [i] physical and cognitive functions and [ii] brain volume of older adults compared to a usual care control group. Thirty-seven healthy and independently living older adults aged 65 years and older were randomly assigned to an intervention (exergame training) or a control (usual care) group. Over 16 weeks, the participants of the intervention group absolved three home-based exergame sessions per week (à 30-40 min) including Tai Chi-inspired exercises, dancing and step-based cognitive games. The control participants continued with their normal daily living. Pre- and post-measurements included assessments of physical (gait parameters, functional muscle strength, balance, aerobic endurance) and cognitive (processing speed, short-term attention span, working memory, inhibition, mental flexibility) functions. T1-weighted magnetic resonance imaging was conducted to assess brain volume. Thirty-one participants (mean age = 73.9 ± 6.4 years, range = 65-90 years, 16 female) completed the study. Inhibition and working memory significantly improved post-intervention in favor of the intervention group [inhibition:
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.