Evidence map›Paper›PMID 32047670›Full record

ArticleInternational journal of hepatology2020

Fecal Microbiota Transplantation for Clostridioides Difficile Infection in Patients with Chronic Liver Disease.

Alireza Meighani, Maryam Alimirah, Mayur Ramesh, Reena Salgia

Open access · goldAbstract read
In one paragraph

Article in International journal of hepatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.4field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
  7. Review
  8. Review
  9. The Role of Gut-Derived Lipopolysaccharides and the Intestinal Barrier in Fatty Liver Diseases.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2022
    Review
  10. Review
  11. Fecal Microbiota Transplantation Is Safe and Effective in Patients With Clostridioides difficile Infection and Cirrhosis.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2021
    Observational
  12. Review
  13. Review
  14. Review
  15. Role of Microbiota in Pathogenesis and Management of Viral Hepatitis.Frontiers in cellular and infection microbiology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Alireza MeighaniDivision of Gastroenterology and Hepatology, Henry Ford Hospital, 2799 W. Grand Blvd, Detroit, MI 48202, USA.ORCID https://orcid.org/0000-0002-0990-2647
Maryam AlimirahDepartment of Internal Medicine, Henry Ford Hospital, 2799 W. Grand Blvd, Detroit, MI 48202, USA.ORCID https://orcid.org/0000-0003-3057-2475
Mayur RameshDivision of Infectious Diseases, Henry Ford Hospital, 2799 W. Grand Blvd, Detroit, MI 48202, USA.
Reena SalgiaDivision of Gastroenterology and Hepatology, Henry Ford Hospital, 2799 W. Grand Blvd, Detroit, MI 48202, USA.
Henry Ford Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFecal microbiota transplantation (FMT) is a well-established therapeutic option for patients with antibiotic resistant

aimsWe studied the effect of FMT on chronic liver disease (CLD) patients with CDI at our tertiary medical center.

methodsA cohort of all patients who received FMT from December 2012 to May 2014 for refractory or recurrent CDI was identified. Patients were monitored for a year after FMT. Descriptive analysis was conducted to compare the effect of FMT in patients with and without CLD.

resultsA total of 201 patients with CDI received FMT, 14 of which had a history of CLD. Nine of these patients exhibited cirrhosis of the liver with a mean Child-Turcotte-Pugh score of 8. CDI development in these patients was associated with recent exposure to antibiotics and was observed to be significantly different between both groups (17% of CLD patients vs. 58% in the general cohort,

conclusionFMT is a safe and effective therapy against CDI for patients with CLD and cirrhosis.

Identifiers

PMID32047670
PMCPMC7007953
OpenAlexW3004183050

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.