Evidence map›Paper›PMID 32047617›Full record

ReviewF1000Research2020

Advances in the pathophysiology of adult-onset focal dystonias: recent neurophysiological and neuroimaging evidence.

Antonella Conte, Giovanni Defazio, Marcello Mascia, Daniele Belvisi, Patrizia Pantano, Alfredo Berardelli

Abstract readReview
In one paragraph

Review in F1000Research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Brain network pathophysiology in dystonia.Dystonia (Lausanne, Switzerland) · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Dual task gait deteriorates gait performance in cervical dystonia patients: a pilot study.Journal of neural transmission (Vienna, Austria : 1996) · 2021
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Antonella ConteDepartment of Human Neurosciences, Sapienza, University of Rome, Rome, Italy.
Giovanni DefazioDepartment of Medical Sciences and Public Health, Neurology Unit, University of Cagliari and AOU Cagliari, Monserrato, Cagliari, Italy.
Marcello MasciaDepartment of Medical Sciences and Public Health, Neurology Unit, University of Cagliari and AOU Cagliari, Monserrato, Cagliari, Italy.
Daniele BelvisiIRCCS Neuromed, Pozzilli (IS), Italy.
Patrizia PantanoDepartment of Human Neurosciences, Sapienza, University of Rome, Rome, Italy.
Alfredo BerardelliDepartment of Human Neurosciences, Sapienza, University of Rome, Rome, Italy.ORCID 0000-0003-3598-3142

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Focal dystonia is a movement disorder characterized by involuntary muscle contractions that determine abnormal postures. The traditional hypothesis that the pathophysiology of focal dystonia entails a single structural dysfunction (i.e. basal ganglia) has recently come under scrutiny. The proposed network disorder model implies that focal dystonias arise from aberrant communication between various brain areas. Based on findings from animal studies, the role of the cerebellum has attracted increased interest in the last few years. Moreover, it has been increasingly reported that focal dystonias also include nonmotor disturbances, including sensory processing abnormalities, which have begun to attract attention. Current evidence from neurophysiological and neuroimaging investigations suggests that cerebellar involvement in the network and mechanisms underlying sensory abnormalities may have a role in determining the clinical heterogeneity of focal dystonias.

Indexed as

Dystonic DisordersAnimalsBrainCerebellumHumansNeuroimagingdystoniamagnetic resonance; pathophysiologyneuroimagingneurophysiology

Identifiers

PMID32047617
PMCPMC6993830

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.