Evidence map›Paper›PMID 32047602›Full record

ArticleF1000Research2019

Learning from cases: Analysis of two cases of craniopharyngioma from the 19

John R Apps, J Ciaran Hutchinson, Susan Shelmerdine, Alex Virasami, Eduard Winter, Thomas S Jacques, Juan-Pedro Martinez-Barbera, Owen Arthurs, Thomas Czech

Abstract readHistorical Article
PubMed Full text at PMC Publisher
In one paragraph

Article in F1000Research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Case-based review: Craniopharyngioma treated with intracystic peginterferon.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

John R Apps *UCL Great Ormond Street Institute of Child Health, UCL, London, UK.ORCID 0000-0001-7902-482X
J Ciaran Hutchinson *UCL Great Ormond Street Institute of Child Health, UCL, London, UK.
Susan ShelmerdineGreat Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
Alex VirasamiGreat Ormond Street Hospital for Children NHS Foundation Trust, London, UK.
Eduard WinterNatural History Museum, Vienna, Austria.
Thomas S JacquesUCL Great Ormond Street Institute of Child Health, UCL, London, UK.ORCID 0000-0002-7833-2158
Juan-Pedro Martinez-BarberaUCL Great Ormond Street Institute of Child Health, UCL, London, UK.
Owen ArthursUCL Great Ormond Street Institute of Child Health, UCL, London, UK.
Thomas CzechMedical University Vienna, Vienna, Austria.

Funding

Cancer Research UK 27727Cancer Research UK 28160Department of Health CDF-2017-10-037Department of Health NIHR-CS-012-002Medical Research Council MR/M000125/1Medical Research Council MR/R002118/1Medical Research Council MR/R00218/1
6 · The paper itself

Abstract

This manuscript describes the study of two cases of craniopharyngioma, which have been examined repeatedly over three separate centuries. This includes analysis by Josef Engel in 1839, who sought to uncover the physiological role of the pituitary gland; Jacob Erdheim in 1904, who initially described the disease we now call craniopharyngioma, and recent high resolution MRI and micro-CT imaging and attempted DNA analyses of the tumours. The cases highlight how, rightly or wrongly, our interpretation of data is shaped by the technologies, methodologies and prevailing theories of a given time.

Indexed as

CraniopharyngiomaPituitary NeoplasmsHistory, 19th CenturyHistory, 20th CenturyHistory, 21st CenturyHumansMagnetic Resonance ImagingCraniopharyngioomaEngelErdheimhistoricalmicro-CT

Identifiers

PMID32047602
PMCPMC6993819

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.