Evidence map›Paper›PMID 32047597›Full record

ReviewF1000Research2019

Mycobacterial virulence: impact on immunogenicity and vaccine research.

Vera M Kroesen, Jan Madacki, Wafa Frigui, Fadel Sayes, Roland Brosch

Open access · goldAbstract readReview
In one paragraph

Review in F1000Research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 24 citations in OpenAlex.

  1. A Pilot Proteomics Analysis ofInternational journal of molecular sciences · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Biotechnologia · 2025
    Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. EspB and HtpG interact with the type III-A CRISPR/Cas system ofFrontiers in molecular biosciences · 2023
    Article
  11. Cyclic-di-AMP Phosphodiesterase Elicits Protective Immune Responses AgainstFrontiers in cellular and infection microbiology · 2022
    Article
  12. Effects ofAnnals of translational medicine · 2022
    Article
  13. Article
  14. Pan and Core Genome Analysis of 183Antibiotics (Basel, Switzerland) · 2021
    Article
  15. Article
  16. Enhancement of CD4Frontiers in cellular and infection microbiology · 2021
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 2 countries.

Vera M KroesenUnit for Integrated Mycobacterial Pathogenomics, CNRS UMR 3525, Institut Pasteur, Paris, France.
Jan MadackiUnit for Integrated Mycobacterial Pathogenomics, CNRS UMR 3525, Institut Pasteur, Paris, France.
Wafa FriguiUnit for Integrated Mycobacterial Pathogenomics, CNRS UMR 3525, Institut Pasteur, Paris, France.ORCID 0000-0001-5172-7961
Fadel SayesUnit for Integrated Mycobacterial Pathogenomics, CNRS UMR 3525, Institut Pasteur, Paris, France.ORCID 0000-0001-7928-6643
Roland BroschUnit for Integrated Mycobacterial Pathogenomics, CNRS UMR 3525, Institut Pasteur, Paris, France.ORCID 0000-0003-2587-3863
Centre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The borderline between virulence and efficacy in live attenuated vaccine strains is often blurred and this is also the case for the Bacillus Calmette-Guérin (BCG), the only currently licensed anti-tuberculosis vaccine used on a large, global scale, which was obtained almost 100 years ago. While BCG is more than 99% identical at the genome level to

Indexed as

Immunogenicity, VaccineBCG VaccineHumansMycobacterium tuberculosisSignal TransductionTuberculosisTuberculosis VaccinesVirulenceVirulence FactorsBCG VaccineTuberculosis VaccinesVirulence Factorshost adaptionmycobacteriapathogen evolution. vaccinationtuberculosisvirulence

Identifiers

PMID32047597
PMCPMC6979476
OpenAlexW2989962550

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.