Evidence map›Paper›PMID 32047245›Full record

ArticleScientific reports2020

Effects of exogenous testosterone application on network connectivity within emotion regulation systems.

Mikhail Votinov, Lisa Wagels, Felix Hoffstaedter, Thilo Kellermann, Katharina S Goerlich, Simon B Eickhoff, Ute Habel

Abstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  18. Hormonal abnormalities in alexithymia.Frontiers in psychiatry · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mikhail VotinovDepartment of Psychiatry, Psychotherapy and Psychosomatics, Medical Faculty, RWTH Aachen University, 52074, Aachen, Germany. mvotinov@ukaachen.de.
Lisa WagelsDepartment of Psychiatry, Psychotherapy and Psychosomatics, Medical Faculty, RWTH Aachen University, 52074, Aachen, Germany.
Felix HoffstaedterInstitute of Neuroscience and Medicine (INM-7), Research Centre Jülich, Jülich, Germany.
Thilo KellermannDepartment of Psychiatry, Psychotherapy and Psychosomatics, Medical Faculty, RWTH Aachen University, 52074, Aachen, Germany.ORCID http://orcid.org/0000-0003-4081-5581
Katharina S GoerlichDepartment of Biomedical Sciences of Cells & Systems, Section Cognitive Neuroscience, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
Simon B EickhoffInstitute of Neuroscience and Medicine (INM-7), Research Centre Jülich, Jülich, Germany.
Ute HabelDepartment of Psychiatry, Psychotherapy and Psychosomatics, Medical Faculty, RWTH Aachen University, 52074, Aachen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Studies with steroid hormones underlined the vital role of testosterone on social-emotional processing. However, there is still a lack of studies investigating whether testosterone modulates network connectivity during resting-state. Here, we tested how the exogenous application of testosterone would affect functional connectivity between regions implicated in emotion regulation. In total, 96 male participants underwent resting-state fMRI scanning. Before the measurement, half of the subjects received 5 g Testim

Indexed as

AndrogensBrainBrain MappingEmotional RegulationEmotionsHumansMagnetic Resonance ImagingMaleNeural PathwaysTestosteroneAndrogensTestosterone

Identifiers

PMID32047245
PMCPMC7012825

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.