Evidence map›Paper›PMID 32047140›Full record

ArticleAging2020

A nomogram combining long non-coding RNA expression profiles and clinical factors predicts survival in patients with bladder cancer.

Yifan Wang, Lutao Du, Xuemei Yang, Juan Li, Peilong Li, Yinghui Zhao, Weili Duan, Yingjie Chen, Yunshan Wang, Haiting Mao and 1 more

Abstract read
In one paragraph

Article in Aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yifan WangDepartment of Clinical Laboratory, The Second Hospital of Shandong University, Jinan, Shandong, China.
Lutao DuDepartment of Clinical Laboratory, The Second Hospital of Shandong University, Jinan, Shandong, China.
Xuemei YangDepartment of Clinical Laboratory, The Second Hospital of Shandong University, Jinan, Shandong, China.
Juan LiDepartment of Clinical Laboratory, The Second Hospital of Shandong University, Jinan, Shandong, China.
Peilong LiDepartment of Clinical Laboratory, The Second Hospital of Shandong University, Jinan, Shandong, China.
Yinghui ZhaoDepartment of Clinical Laboratory, The Second Hospital of Shandong University, Jinan, Shandong, China.
Weili DuanDepartment of Clinical Laboratory, The Second Hospital of Shandong University, Jinan, Shandong, China.
Yingjie ChenDepartment of Clinical Laboratory, The Second Hospital of Shandong University, Jinan, Shandong, China.
Yunshan WangDepartment of Clinical Laboratory, The Second Hospital of Shandong University, Jinan, Shandong, China.
Haiting MaoDepartment of Clinical Laboratory, The Second Hospital of Shandong University, Jinan, Shandong, China.
Chuanxin WangDepartment of Clinical Laboratory, The Second Hospital of Shandong University, Jinan, Shandong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bladder cancer (BCa) is a heterogeneous disease with various tumorigenic mechanisms and clinical behaviors. The current tumor-node-metastasis (TNM) staging system is inadequate to predict overall survival (OS) in BCa patients. We developed a BCa-specific, long-non-coding-RNA (lncRNA)-based nomogram to improve survival prediction in BCa. We obtained the large-scale gene expression profiles of samples from 414 BCa patients in The Cancer Genome Atlas database. Using an lncRNA-mining computational framework, we identified three OS-related lncRNAs among 826 lncRNAs that were differentially expressed between BCa and normal samples. We then constructed a three-lncRNA signature, which efficiently distinguished high-risk from low-risk patients and was even viable in the TNM stage-II, TNM stage-III and ≥65-year-old subgroups (all

Indexed as

NomogramsAgedCell MovementFemaleGene Expression Regulation, NeoplasticHumansMaleMiddle AgedPrognosisRisk FactorsRNA, Long NoncodingUrinary Bladder NeoplasmsRNA, Long Noncodingbladder cancerlong non-coding RNAnomogramscore systemsurvival

Identifiers

PMID32047140
PMCPMC7041749

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.