Evidence map›Paper›PMID 32047125›Full record

ArticlemBio2020

Molecular Determinants of Substrate Selectivity of a Pneumococcal Rgg-Regulated Peptidase-Containing ABC Transporter.

Charles Y Wang, Jennifer S Medlin, Don R Nguyen, W Miguel Disbennett, Suzanne Dawid

Open access · goldAbstract read
In one paragraph

Article in mBio, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. The MutRS quorum-sensing system controls lantibiotic mutacin production in the human pathogenProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Intraspecific Diversity of Microbial Anti-Inflammatory Molecule (MAM) fromInternational journal of molecular sciences · 2022
    Article
  15. Article
  16. Article
  17. The pneumococcal social network.PLoS pathogens · 2020
    Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Charles Y WangDepartment of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, USA.
Jennifer S MedlinDepartment of Pediatrics, University of Michigan, Ann Arbor, Michigan, USA.
Don R NguyenDepartment of Pediatrics, University of Michigan, Ann Arbor, Michigan, USA.
W Miguel DisbennettDepartment of Pediatrics, University of Michigan, Ann Arbor, Michigan, USA.
Suzanne DawidDepartment of Microbiology and Immunology, University of Michigan, Ann Arbor, Michigan, USA sdawid@umich.edu.ORCID 0000-0001-8921-0386
University of Michigan · US

Funding

MICHIGAN MEDICAL SCIENTIST TRAINING PROGRAMT32GM007863 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI COLLINS, KATHLEEN L. · 1985 to 2024
$38.3M
Molecular Mechanisms of Microbial Pathogenesis Training ProgramT32AI007528 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CARRUTHERS, VERNON BRUCE · 1998 to 2024
$6.8M
Coordinate regulation of competence and pneumocin production in S. pneumoniaeR01AI101285 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DAWID, SUZANNE RACHEL · 2013 to 2017
$1.9M
Coordinate regulation of competence and pneumocin production in S. pneumoniaeR56AI101285 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DAWID, SUZANNE RACHEL · 2018 to 2018
$383k
NIAID NIH HHS R01 AI101285NIAID NIH HHS R56 AI101285NIAID NIH HHS T32 AI007528NIGMS NIH HHS T32 GM007863
6 · The paper itself

Abstract

Peptidase-containing ABC transporters (PCATs) are a widely distributed family of transporters which secrete double-glycine (GG) peptides. In the opportunistic pathogen

Indexed as

AnimalsATP-Binding Cassette TransportersBacterial ProteinsBiological TransportFemaleGene Expression Regulation, BacterialMiceMice, Inbred BALB CNasopharynxPeptidesPheromonesQuorum SensingStreptococcus pneumoniaeSubstrate SpecificityTrans-ActivatorsATP-Binding Cassette TransportersBacterial ProteinsPeptidesPheromonesrgg protein, StreptococcusTrans-ActivatorsABC transportersbacteriocinsquorum sensingStreptococcus pneumoniae

Identifiers

PMID32047125
PMCPMC7018657
OpenAlexW3006329125

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.