Evidence map›Paper›PMID 32047008›Full record

ArticleBMJ open2020

Neighbourhood socioeconomic status modifies the association between anxiety and depression during pregnancy and preterm birth: a Community-based Canadian cohort study.

Kamala Adhikari, Scott B Patten, Tyler Williamson, Alka B Patel, Shahirose Premji, Suzanne Tough, Nicole Letourneau, Gerald Giesbrecht, Amy Metcalfe

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Kamala AdhikariDepartment of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada kamala.adhikaridahal@ucalgary.ca.ORCID 0000-0003-2872-9496
Scott B PattenDepartment of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
Tyler WilliamsonDepartment of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
Alka B PatelDepartment of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
Shahirose PremjiSchool of Nursing, Faculty of Health, York University, Calgary, Alberta, Canada.
Suzanne ToughDepartment of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
Nicole LetourneauDepartment of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
Gerald GiesbrechtDepartment of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
Amy MetcalfeDepartment of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
University of Calgary · CAAlberta Health Services · CAYork University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study examined the association of anxiety alone, depression alone and the presence of both anxiety and depression with preterm birth (PTB) and further examined whether neighbourhood socioeconomic status (SES) modified this association.

designCohort study using individual-level data from two community-based prospective pregnancy cohort studies (All Our Families; AOF) and Alberta Pregnancy Outcomes and Nutrition (APrON) and neighbourhood SES data from the 2011 Canadian census.

settingCalgary, Alberta, Canada.

participantsOverall, 5538 pregnant women who were <27 weeks of gestation and >15 years old were enrolled in the cohort studies between 2008 and 2012. 3341 women participated in the AOF study and 2187 women participated in the APrON study, with 231 women participated in both studies. Women who participated in both studies were only counted once. PRIMARY AND SECONDARY OUTCOME MEASURES: PTB was defined as delivery prior to 37 weeks of gestation. Depression was defined as an Edinburgh Postnatal Depression Scale (EPDS) score of ≥13, anxiety was defined as an EPDS-anxiety subscale score of ≥6, and the presence of both anxiety and depression was defined as meeting both anxiety and depression definitions.

resultsOverall, 7.3% of women delivered preterm infants. The presence of both anxiety and depression, but neither of these conditions alone, was significantly associated with PTB (OR 1.6, 95% CI 1.1 to 2.3) and had significant interaction with neighbourhood deprivation (p=0.004). The predicted probability of PTB for women with both anxiety and depression was 10.0%, which increased to 15.7% if they lived in the most deprived neighbourhoods and decreased to 1.4% if they lived in the least deprived neighbourhoods.

conclusionsEffects of anxiety and depression on risk of PTB differ depending on where women live. This understanding may guide the identification of women at increased risk for PTB and allocation of resources for early identification and management of anxiety and depression.

Indexed as

AnxietyDepressionPregnancy ComplicationsPremature BirthSocioeconomic FactorsAdultCanadaCohort StudiesEffect Modifier, EpidemiologicFemaleHumansMental HealthPregnancyPregnancy OutcomeResidence CharacteristicsRisk Assessmentepidemiologymental healthneighbourhood socioeconomic statuspreterm birth

Identifiers

PMID32047008
PMCPMC7045250
OpenAlexW3005287527

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.