Evidence map›Paper›PMID 32046989›Full record

ArticleEvidence-based mental health2020

Natural language processing for structuring clinical text data on depression using UK-CRIS.

Nemanja Vaci, Qiang Liu, Andrey Kormilitzin, Franco De Crescenzo, Ayse Kurtulmus, Jade Harvey, Bessie O'Dell, Simeon Innocent, Anneka Tomlinson, Andrea Cipriani and 1 more

Abstract read
In one paragraph

Article in Evidence-based mental health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Big data and psychiatry: advances, constraints and future directions.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2026
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  16. Artificial intelligence for dementia-Applied models and digital health.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023
    Review
  17. Artificial intelligence for dementia prevention.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Nemanja VaciDepartment of Psychiatry, University of Oxford, Oxford, Oxfordshire, UK nemanja.vaci@psych.ox.ac.uk.ORCID http://orcid.org/0000-0002-8094-0902
Qiang LiuDepartment of Psychiatry, University of Oxford, Oxford, Oxfordshire, UK.
Andrey KormilitzinDepartment of Psychiatry, University of Oxford, Oxford, Oxfordshire, UK.
Franco De CrescenzoDepartment of Psychiatry, University of Oxford, Oxford, Oxfordshire, UK.
Ayse KurtulmusDepartment of Psychiatry, University of Oxford, Oxford, Oxfordshire, UK.
Jade HarveyResearch and Development, Oxford Health NHS Foundation Trust, Oxford, Oxfordshire, UK.
Bessie O'DellDepartment of Psychiatry, University of Oxford, Oxford, Oxfordshire, UK.
Simeon InnocentDepartment of Psychiatry, University of Oxford, Oxford, Oxfordshire, UK.
Anneka TomlinsonDepartment of Psychiatry, University of Oxford, Oxford, Oxfordshire, UK.
Andrea CiprianiDepartment of Psychiatry, University of Oxford, Oxford, Oxfordshire, UK.ORCID http://orcid.org/0000-0001-5179-8321
Alejo Nevado-HolgadoDepartment of Psychiatry, University of Oxford, Oxford, Oxfordshire, UK.

Funding

Medical Research Council MC_PC_17215
6 · The paper itself

Abstract

backgroundUtilisation of routinely collected electronic health records from secondary care offers unprecedented possibilities for medical science research but can also present difficulties. One key issue is that medical information is presented as free-form text and, therefore, requires time commitment from clinicians to manually extract salient information. Natural language processing (NLP) methods can be used to automatically extract clinically relevant information.

objectiveOur aim is to use natural language processing (NLP) to capture real-world data on individuals with depression from the Clinical Record Interactive Search (CRIS) clinical text to foster the use of electronic healthcare data in mental health research.

methodsWe used a combination of methods to extract salient information from electronic health records. First, clinical experts define the information of interest and subsequently build the training and testing corpora for statistical models. Second, we built and fine-tuned the statistical models using active learning procedures.

findingsResults show a high degree of accuracy in the extraction of drug-related information. Contrastingly, a much lower degree of accuracy is demonstrated in relation to auxiliary variables. In combination with state-of-the-art active learning paradigms, the performance of the model increases considerably.

conclusionsThis study illustrates the feasibility of using the natural language processing models and proposes a research pipeline to be used for accurately extracting information from electronic health records. CLINICAL IMPLICATIONS: Real-world, individual patient data are an invaluable source of information, which can be used to better personalise treatment.

Indexed as

Data MiningDepressionDepressive DisorderElectronic Health RecordsNatural Language ProcessingFeasibility StudiesHumansModels, StatisticalUnited Kingdomadult psychiatry

Identifiers

PMID32046989
PMCPMC10231554

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.