Evidence map›Paper›PMID 32046849›Full record

ArticleMethods in enzymology2020

Methods for studying human sirtuins with activity-based chemical probes.

Song Zheng, Jessica Wohlfahrt, Ian Cohen, Yana Cen

Abstract read
In one paragraph

Article in Methods in enzymology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Song ZhengDepartment of Pharmaceutical Sciences, Albany College of Pharmacy and Health Sciences, Colchester, VT, United States.
Jessica WohlfahrtDepartment of Pharmaceutical Sciences, Albany College of Pharmacy and Health Sciences, Colchester, VT, United States.
Ian CohenDepartment of Pharmaceutical Sciences, Albany College of Pharmacy and Health Sciences, Colchester, VT, United States.
Yana CenDepartment of Pharmaceutical Sciences, Albany College of Pharmacy and Health Sciences, Colchester, VT, United States. Electronic address: ceny2@vcu.edu.

Funding

Novel Probes for Sirtuins: A Chemical Biology ApproachR15GM123393 · NIGMS · ALBANY COLLEGE OF PHARMACY · PI HASS, MARTHA A. · 2017 to 2017
$480k
NIGMS NIH HHS R15 GM123393
6 · The paper itself

Abstract

Sirtuins are unique posttranslational modification enzymes that utilize NAD

Indexed as

Click ChemistrySirtuinsHumansLysinePeptidesProtein Processing, Post-TranslationalLysinePeptidesSirtuinsActivity-based chemical probesNAD(+)-dependentSirtuin

Identifiers

PMID32046849
PMCPMC7027925

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.