Evidence map›Paper›PMID 32046705›Full record

ArticleBMC complementary medicine and therapies2020

Antiviral activities of Radix isatidis polysaccharide against pseudorabies virus in swine testicle cells.

Chao Tong, Zewen Chen, Fang Liu, Yanyan Qiao, Tong Chen, Xuebing Wang

Open access · goldAbstract read
In one paragraph

Article in BMC complementary medicine and therapies, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 45 citations in OpenAlex.

  1. Review
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  4. Effect of miR-17 onFrontiers in veterinary science · 2024
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  5. Extract ofAntioxidants (Basel, Switzerland) · 2023
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  8. Decoding cancer and herbal renaissance.Longhua Chinese medicine · 2022
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  11. Antiviral Activity ofOxidative medicine and cellular longevity · 2022
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  12. Article
  13. Polysaccharide Nanoparticles fromNanomaterials (Basel, Switzerland) · 2021
    Article
  14. Article
  15. Review
  16. Review
  17. Frontiers in nutrition · 2021
    Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Chao TongCollege of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450000, China.
Zewen ChenCollege of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450000, China.
Fang LiuCollege of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450000, China.
Yanyan QiaoCollege of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450000, China.
Tong ChenCollege of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450000, China.
Xuebing WangCollege of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhengzhou, 450000, China. xbwang74@163.com.
Henan Agricultural University · CN

Funding

Henan Province Industry-University-Research Cooperation Project 172107000011
6 · The paper itself

Abstract

backgroundRadix isatidis has been used in China and other Asian countries for its antiviral and anti-inflammatory effects for thousands of years. However, the antiviral effect of Radix isatidis polysaccharide against pseudorabies virus (PRV) is still unknown.

methodsThe polysaccharide were isolated from extract of the roots of Radix isatidis. MTT assays were used to determine the preventive effect, inhibitory effect and antiviral effect of Radix isatidis polysaccharide on PRV in vitro.

resultsThis study found that different concentrations of polysaccharides from this plant can inhibit PRV replication by 14.674-30.840%, prevent infection at rates of 6.668-14.923%, and kill this virus at rates of 32.214-67.422%.

conclusionThese results broaden the understanding of this traditional Chinese herb and provide a theoretical basis for further research. Moreover, Radix isatidis polysaccharide could be used for antiviral therapy.

Indexed as

AnimalsAntiviral AgentsCell LineCells, CulturedChinaDrugs, Chinese HerbalHerpesvirus 1, SuidIsatisMalePlant RootsPolysaccharidesSwineTestisVirus ReplicationAntiviral AgentsbanlangenDrugs, Chinese HerbalPolysaccharidesPolysaccharidePseudorabies virusRadix isatidisSwine testicle cells

Identifiers

PMID32046705
PMCPMC7076820
OpenAlexW3007888753

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.