Evidence map›Paper›PMID 32046688›Full record

ArticleBMC complementary medicine and therapies2020

Ginsenosides induce extensive changes in gene expression and inhibit oxidative stress-induced apoptosis in human lens epithelial cells.

Zhewen Wang, Shiping Zhou, Xiaoqing Hu, Jiannan Chai

Open access · goldAbstract read
In one paragraph

Article in BMC complementary medicine and therapies, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Zhewen WangDepartment of Ophthalmology, First Hospital of Jilin University, No.1 Xinmin Avenue, Changchun, 130021, China.
Shiping ZhouEndoscopy Center, First Hospital of Jilin University, Changchun, 130021, China.
Xiaoqing HuDepartment of Ophthalmology, First Hospital of Jilin University, No.1 Xinmin Avenue, Changchun, 130021, China. huxq2003@163.com.ORCID http://orcid.org/0000-0002-7545-0968
Jiannan ChaiDepartment of Clinical Laboratory, First Hospital of Jilin University, No.1 Xinmin Avenue, Changchun, 130021, China. cjn0223@163.com.
Jilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe effect of ginsenosides on the growth and apoptosis of human lens epithelial (HLE) B3 cells exposed to H

methodsHLE-B3 cells were treated with 1.75 M H

resultsAddition of ginsenosides significantly alleviated the growth inhibitory effect of H

conclusionGinsenosides induce extensive changes in the expression of genes involved in multiple signaling pathways, including apoptotic signaling pathway and DNA damage response signaling pathway. Ginsenosides alleviate H

Indexed as

ApoptosisCell LineEpithelial CellsFlow CytometryGene ExpressionGinsenosidesHumansLens, CrystallinePanax notoginsengGinsenosidesGinsenosidesH2O2HLE-B3 cells

Identifiers

PMID32046688
PMCPMC7076854
OpenAlexW3008809114

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.