Evidence map›Paper›PMID 32046584›Full record

ArticleNeurocase2020

Bilateral basal ganglia infarcts presenting as rapid onset cognitive and behavioral disturbance.

Joanna Hellmuth, Kaitlin Casaletto, Richard Cuneo, Katherine L Possin, William Dillon, Michael D Geschwind

Open access · greenAbstract readCase Reports
In one paragraph

Article in Neurocase, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Joanna HellmuthMemory and Aging Center, Department of Neurology, University of California, San Francisco, CA, USA.
Kaitlin CasalettoMemory and Aging Center, Department of Neurology, University of California, San Francisco, CA, USA.
Richard CuneoDepartment of Neurology, University of California, San Francisco, CA, USA.
Katherine L PossinMemory and Aging Center, Department of Neurology, University of California, San Francisco, CA, USA.
William DillonDepartment of Radiology, University of California, San Francisco, CA, USA.
Michael D GeschwindMemory and Aging Center, Department of Neurology, University of California, San Francisco, CA, USA.
University of California, San Francisco · USUniversity Memory and Aging Center · US

Funding

TDP-43 Loss-of-Function: Biology to BiomarkersP01AG019724 · NIA · UNIVERSITY OF PENNSYLVANIA · PI Jennifer Merrilees · 2002 to 2026
$67.2M
Research Education ComponentP30AG062422 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Serggio Carlo Lanata · 2019 to 2026
$36.9M
Multidisciplinary Research Fellowship in Alzheimer’s disease and Related DementiasT32AG023481 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BRUCE L MILLER, HOWARD J ROSEN · 2005 to 2026
$7.4M
Predicting progression of human prion diseaseR01AG031189 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GESCHWIND, MICHAEL D · 2008 to 2017
$5.7M
Tracking longitudinal change in presymptomatic genetic prion disease (TLC-Pre-gPrD)R01AG062562 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GESCHWIND, MICHAEL D · 2019 to 2023
$5.4M
The UCSF Brain Health Assessment for the Detection of Cognitive Impairment Among Diverse Populations in Primary CareUG3NS105557 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI POSSIN, KATHERINE LAUREL · 2017 to 2018
$2.4M
Can Behavior Shape Neural Health? Identifying Modifiable Factors to Prevent Cognitive Decline in AgeK23AG058752 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CASALETTO, KAITLIN B · 2018 to 2022
$994k
Defining the clinical utility of CSF biomarkers of neurodegeneration in HIV+ eldersK23MH114724 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HELLMUTH, JOANNA · 2017 to 2020
$796k
NIA NIH HHS K23 AG058752NIA NIH HHS P01 AG019724NIA NIH HHS P30 AG062422NIA NIH HHS R01 AG031189NIA NIH HHS R01 AG062562NIA NIH HHS T32 AG023481NIMH NIH HHS K23 MH114724NINDS NIH HHS UG3 NS105557
6 · The paper itself

Abstract

We describe a rare case of a patient with rapid onset, prominent cognitive and behavioral changes who presented to our rapidly progressive dementia program with symptoms ultimately attributed to bilateral basal ganglia infarcts involving the caudate heads. We review the longitudinal clinical presentation and neuropsychological testing for this patient, and discuss the implicated basal ganglia and frontal lobe neuroanatomy.

Indexed as

Basal Ganglia DiseasesBehavioral SymptomsCerebral InfarctionCognitive DysfunctionAged, 80 and overCaudate NucleusExecutive FunctionHumansMaleMemory, Short-TermSpace PerceptionBilateral basal gangliacaudate headexecutive functionfrontal lobe syndromespatial working memory

Identifiers

PMID32046584
PMCPMC7377550
OpenAlexW3006239452

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.