Evidence map›Paper›PMID 32046360›Full record

ReviewNutrients2020

The Role of Dietary Antioxidants in the Pathogenesis of Neurodegenerative Diseases and Their Impact on Cerebral Oxidoreductive Balance.

Anna Winiarska-Mieczan, Ewa Baranowska-Wójcik, Małgorzata Kwiecień, Eugeniusz R Grela, Dominik Szwajgier, Katarzyna Kwiatkowska, Bożena Kiczorowska

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 57 citations in OpenAlex.

  1. Article
  2. Food science & nutrition · 2026
    Article
  3. Review
  4. Investigating the Potential of Essential Oils fromPlants (Basel, Switzerland) · 2024
    Article
  5. Review
  6. Review
  7. Artificial Intelligence in The Management of Neurodegenerative Disorders.CNS & neurological disorders drug targets · 2024
    Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Towards early detection of neurodegenerative diseases: A gut feeling.Frontiers in cell and developmental biology · 2023
    Review
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Anna Winiarska-MieczanDepartment of Bromatology and Food Physiology, University of Life Sciences in Lublin, 20-950 Lublin, Poland.
Ewa Baranowska-WójcikDepartment of Biotechnology, Microbiology and Human Nutrition, University of Life Sciences in Lublin, 20-950 Lublin, Poland.
Małgorzata KwiecieńDepartment of Bromatology and Food Physiology, University of Life Sciences in Lublin, 20-950 Lublin, Poland.
Eugeniusz R GrelaDepartment of Bromatology and Food Physiology, University of Life Sciences in Lublin, 20-950 Lublin, Poland.
Dominik SzwajgierDepartment of Biotechnology, Microbiology and Human Nutrition, University of Life Sciences in Lublin, 20-950 Lublin, Poland.
Katarzyna KwiatkowskaDepartment of Bromatology and Food Physiology, University of Life Sciences in Lublin, 20-950 Lublin, Poland.
Bożena KiczorowskaDepartment of Bromatology and Food Physiology, University of Life Sciences in Lublin, 20-950 Lublin, Poland.
University of Life Sciences in Lublin · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neurodegenerative diseases are progressive diseases of the nervous system that lead to neuron loss or functional disorders. Neurodegenerative diseases require long-term, sometimes life-long pharmacological treatment, which increases the risk of adverse effects and a negative impact of pharmaceuticals on the patients' general condition. One of the main problems related to the treatment of this type of condition is the limited ability to deliver drugs to the brain due to their poor solubility, low bioavailability, and the effects of the blood-brain barrier. Given the above, one of the main objectives of contemporary scientific research focuses on the prevention of neurodegenerative diseases. As disorders related to the competence of the antioxidative system are a marker in all diseases of this type, the primary prophylactics should entail the use of exogenous antioxidants, particularly ones that can be used over extended periods, regardless of the patient's age, and that are easily available, e.g., as part of a diet or as diet supplements. The paper analyzes the significance of the oxidoreductive balance in the pathogenesis of neurodegenerative diseases. Based on information published globally in the last 10 years, an analysis is also provided with regard to the impact of exogenous antioxidants on brain functions with respect to the prevention of this type of diseases.

Indexed as

Dietary SupplementsAnimalsAntioxidantsBlood-Brain BarrierBrainFemaleHumansMaleNeurodegenerative DiseasesOxidation-ReductionAntioxidantsdietexogenous antioxidantsneurodegenerative diseasesprevention

Identifiers

PMID32046360
PMCPMC7071337
OpenAlexW3004781703

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.