Evidence map›Paper›PMID 32046141›Full record

ArticleMicromachines2020

Microspinning: Local Surface Mixing via Rotation of Magnetic Microparticles for Efficient Small-Volume Bioassays.

Su Deok Kim, Seo Woo Song, Dong Yoon Oh, Amos Chungwon Lee, Jeong Woo Koo, Taehun Kang, Min Chang Kim, Changhee Lee, Yunjin Jeong, Hyun Yong Jeong and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Micromachines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Su Deok KimInstitutes of Entrepreneurial BioConvergence, Seoul National University, Seoul 08826, Korea.
Seo Woo SongInstitutes of Entrepreneurial BioConvergence, Seoul National University, Seoul 08826, Korea.
Dong Yoon OhInterdisciplinary Program for Bioengineering, Seoul National University, Seoul 08826, Korea.
Amos Chungwon LeeInstitutes of Entrepreneurial BioConvergence, Seoul National University, Seoul 08826, Korea.
Jeong Woo KooDepartment of Material Science and Engineering, Seoul National University, Seoul 08826, Korea.
Taehun KangDepartment of Electrical and Computer Engineering, Seoul National University, Seoul 08826, Korea.
Min Chang KimSchool of Environmental Engineering, University of Seoul, Seoul 08826, Korea.
Changhee LeeInstitutes of Entrepreneurial BioConvergence, Seoul National University, Seoul 08826, Korea.
Yunjin JeongInstitutes of Entrepreneurial BioConvergence, Seoul National University, Seoul 08826, Korea.
Hyun Yong JeongBK21+ Creative Research Engineer Development for IT, Seoul National University, Seoul 08826, Korea.
Daewon LeeBK21+ Creative Research Engineer Development for IT, Seoul National University, Seoul 08826, Korea.
Seongkyu ChoInstitutes of Entrepreneurial BioConvergence, Seoul National University, Seoul 08826, Korea.
Sunghoon KwonInstitutes of Entrepreneurial BioConvergence, Seoul National University, Seoul 08826, Korea.
Jiyun KimSchool of Materials Science and Engineering, Ulsan National Institute of Science and Technology, Ulsan 44919, Korea.

Funding

National Research Foundation of Korea 2015K1A4A3047345National Research Foundation of Korea 2017R1D1A1B03034297National Research Foundation of Korea 2019R1I1A1A01059279Research funds of UNIST 1.180059.01 and 1.160107.01
6 · The paper itself

Abstract

The need for high-throughput screening has led to the miniaturization of the reaction volume of the chamber in bioassays. As the reactor gets smaller, surface tension dominates the gravitational or inertial force, and mixing efficiency decreases in small-scale reactions. Because passive mixing by simple diffusion in tens of microliter-scale volumes takes a long time, active mixing is needed. Here, we report an efficient micromixing method using magnetically rotating microparticles with patterned magnetization induced by magnetic nanoparticle chains. Because the microparticles have magnetization patterning due to fabrication with magnetic nanoparticle chains, the microparticles can rotate along the external rotating magnetic field, causing micromixing. We validated the reaction efficiency by comparing this micromixing method with other mixing methods such as simple diffusion and the use of a rocking shaker at various working volumes. This method has the potential to be widely utilized in suspension assay technology as an efficient mixing strategy.

Indexed as

magnetic particlemagnetization patterningmicromixingmicroparticlesuspension array

Identifiers

PMID32046141
PMCPMC7074623

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.