Evidence map›Paper›PMID 32046135›Full record

ArticleInternational journal of molecular sciences2020

Implication of 5-HT in the Dysregulation of Chloride Homeostasis in Prenatal Spinal Motoneurons from the G93A Mouse Model of Amyotrophic Lateral Sclerosis.

Elodie Martin, William Cazenave, Anne-Emilie Allain, Daniel Cattaert, Pascal Branchereau

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Compensatory scaling of modulatory neural populations in response to motor challenges.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  10. Rate-dependent depression is impaired in amyotrophic lateral sclerosis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
    Article
  11. Serotonin in Health and Disease.International journal of molecular sciences · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Elodie MartinUniversity of Bordeaux, CNRS, INCIA, UMR 5287, F-33000 Bordeaux, France.
William CazenaveUniversity of Bordeaux, CNRS, INCIA, UMR 5287, F-33000 Bordeaux, France.
Anne-Emilie AllainUniversity of Bordeaux, CNRS, INCIA, UMR 5287, F-33000 Bordeaux, France.
Daniel CattaertUniversity of Bordeaux, CNRS, INCIA, UMR 5287, F-33000 Bordeaux, France.ORCID 0000-0003-4471-0525
Pascal BranchereauUniversity of Bordeaux, CNRS, INCIA, UMR 5287, F-33000 Bordeaux, France.ORCID 0000-0003-3972-8229
Centre National de la Recherche Scientifique · FR

Funding

Association pour la recherche sur la Sclérose Latérale Amyotrophique et autres maladies du Motoneurone (ARSLA) 2013 - 2016
6 · The paper itself

Abstract

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by progressive motor neuron degeneration and muscle paralysis. The early presymptomatic onset of abnormal processes is indicative of cumulative defects that ultimately lead to a late manifestation of clinical symptoms. It remains of paramount importance to identify the primary defects that underlie this condition and to determine how these deficits lead to a cycle of deterioration. We recently demonstrated that prenatal E17.5 lumbar spinal motoneurons (MNs) from SOD1

Indexed as

Action PotentialsAmyotrophic Lateral SclerosisAnimalsChloridesFemalegamma-Aminobutyric AcidGlycineHomeostasisK Cl- CotransportersMaleMiceMotor NeuronsSerotoninSpinal CordSuperoxide Dismutase-1SymportersChloridesgamma-Aminobutyric AcidGlycineK Cl- CotransportersSerotoninSod1 protein, mouseSuperoxide Dismutase-1Symporters5-HTALSchloride homeostasisdevelopmentGABA/glycinemotoneuronperforated patch-clampSOD1G93A mousespinal cord

Identifiers

PMID32046135
PMCPMC7039234
OpenAlexW3004962254

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.