Evidence map›Paper›PMID 32046125›Full record

ArticleCancers2020

Effects of Andrographolide on Intracellular pH Regulation, Cellular Migration, and Apoptosis in Human Cervical Cancer Cells †.

Shih-Hurng Loh, Yi-Ting Tsai, Shu-Fu Huang, Tien-Chieh Yu, Pei-Chun Kuo, Shih-Chi Chao, Mei-Fang Chou, Chien-Sung Tsai, Shiao-Pieng Lee

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. An Innovative Method of Improving an Extract ofInternational journal of molecular sciences · 2025
    Article
  3. Article
  4. Article
  5. Life (Basel, Switzerland) · 2021
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Shih-Hurng LohDepartment of Clinical Pharmacy, Tri-Service General Hospital, National Defense Medical Center, Taipei 11490, Taiwan.
Yi-Ting TsaiDivision of Cardiovascular Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei 11490, Taiwan.
Shu-Fu HuangDepartment of Clinical Pharmacy, Tri-Service General Hospital, National Defense Medical Center, Taipei 11490, Taiwan.
Tien-Chieh YuDepartment of Pharmacology, National Defense Medical Center, Taipei 11490, Taiwan.
Pei-Chun KuoDepartment of Pharmacology, National Defense Medical Center, Taipei 11490, Taiwan.
Shih-Chi ChaoGraduate Institute of Life Sciences, National Defense Medical Center, Taipei 11490, Taiwan.
Mei-Fang ChouDepartment of Clinical Pharmacy, Tri-Service General Hospital, National Defense Medical Center, Taipei 11490, Taiwan.
Chien-Sung TsaiDivision of Cardiovascular Surgery, Department of Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei 11490, Taiwan.
Shiao-Pieng LeeDepartment of Biomedical Engineering, National Defense Medical Center, Taipei 11490, Taiwan.
Tri-Service General Hospital · TWNational Defense Medical Center · TW

Funding

National Science Council MOST 106-2320-B-016-003-MY2; MOST 106-2314-B-016 -037 -MY3Tri-Service General Hospital TSGH-C108-008-S05
6 · The paper itself

Abstract

Cancer cells have been characterized with alkaline intracellular pH (pH

Indexed as

andrographolideapoptosisBcl-2human cervical cancer cellsintracellular pHmigrationNa+/H+ exchanger isoform 1PARPpro-Caspase-3

Identifiers

PMID32046125
PMCPMC7072207
OpenAlexW3005360494

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.