Evidence map›Paper›PMID 32046063›Full record

ArticleHigh-throughput2020

Precision Medicine in Non-Communicable Diseases.

Giuseppe Novelli, Michela Biancolella, Andrea Latini, Aldo Spallone, Paola Borgiani, Marisa Papaluca

Open access · goldAbstract read
In one paragraph

Article in High-throughput, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. EngineeredExperimental and therapeutic medicine · 2020
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 4 countries.

Giuseppe NovelliDepartment of Biomedicine & Prevention, Genetics Unit, University of Rome "Tor Vergata", 00133 Rome, Italy.ORCID 0000-0002-7781-602X
Michela BiancolellaDepartment of Biology, University of Rome "Tor Vergata", 00133 Rome, Italy.
Andrea LatiniDepartment of Biomedicine & Prevention, Genetics Unit, University of Rome "Tor Vergata", 00133 Rome, Italy.
Aldo SpalloneDepartment of Neurology and Neurosurgery, Peoples' Friendship University of Russia (RUDN University), Moscow 117198, Russia.
Paola BorgianiDepartment of Biomedicine & Prevention, Genetics Unit, University of Rome "Tor Vergata", 00133 Rome, Italy.
Marisa PapalucaImperial College, Faculty of Medicine, School of Public Health, SW7 2AZ London, UK.
University of Rome Tor Vergata · ITImperial College London · GBPeoples' Friendship University of Russia · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increase in life expectancy during the 20th century ranks as one of society's greatest achievements, with massive growth in the numbers and proportion of the elderly, virtually occurring in every country of the world. The burden of chronic diseases is one of the main consequences of this phenomenon, severely hampering the quality of life of elderly people and challenging the efficiency and sustainability of healthcare systems. Non-communicable diseases (NCDs) are considered a global emergency responsible for over 70% of deaths worldwide. NCDs are also the basis for complex and multifactorial diseases such as hypertension, diabetes, and obesity. The epidemics of NCDs are a consequence of a complex interaction between health, economic growth, and development. This interaction includes the individual genome, the microbiome, the metabolome, the immune status, and environmental factors such as nutritional and chemical exposure. To counteract NCDs, it is therefore essential to develop an innovative, personalized, preventative, early care model through the integration of different molecular profiles of individuals to identify both the critical biomarkers of NCD susceptibility and to discover novel therapeutic targets.

Indexed as

epigeneticsgenomic biomarkersgenomicspharmacogeneticsprecision medicine

Identifiers

PMID32046063
PMCPMC7151056
OpenAlexW3004621509

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.