ArticleNanomaterials (Basel, Switzerland)2020
Removal of Diclofenac, Paracetamol, and Carbamazepine from Model Aqueous Solutions by Magnetic Sol-Gel Encapsulated Horseradish Peroxidase and Lignin Peroxidase Composites.
Article in Nanomaterials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 63 citations in OpenAlex.
- A Biochar-Based Composite Hydrogel Microenvironment for Enhanced Biocatalysis.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Hybrid Double Enzyme Biocatalyst for Effective Degradation of Organic Pollutants.ACS environmental Au · 2025Article
- Paracetamol mineralization strategy in laboratory scale using Aspergillus niger KCAC.International microbiology : the official journal of the Spanish Society for Microbiology · 2024Article
- Natural Silicates Encapsulated Enzymes as Green Biocatalysts for Degradation of Pharmaceuticals.ACS ES&T water · 2024Article
- Environmental concerns and bioaccumulation of psychiatric drugs in water bodies - Conventional versus biocatalytic systems of mitigation.Environmental research · 2023Review
- Role of bio-electrochemical technology for enzyme activity stimulation in high-consumption pharmaceuticals biodegradation.3 Biotech · 2023Review
- Progressive Biocatalysts for the Treatment of Aqueous Systems Containing Pharmaceutical Pollutants.Life (Basel, Switzerland) · 2023Review
- Review
- Structural Rearrangements of Carbonic Anhydrase Entrapped in Sol-Gel Magnetite Determined by ATR-FTIR Spectroscopy.International journal of molecular sciences · 2022Article
- Article
- Removal of Persistent Sulfamethoxazole and Carbamazepine from Water by Horseradish Peroxidase Encapsulated into Poly(Vinyl Chloride) Electrospun Fibers.International journal of molecular sciences · 2021Article
- Magnetic Nanoparticle-Containing Supports as Carriers of Immobilized Enzymes: Key Factors Influencing the Biocatalyst Performance.Nanomaterials (Basel, Switzerland) · 2021Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
Sustainable and green synthesis of nanocomposites for degradation of pharmaceuticals was developed via immobilization and stabilization of the biological strong oxidizing agents, peroxidase enzymes, on a solid support. Sol-gel encapsulated enzyme composites were characterized using electron microscopy (TEM, SEM), atomic force microscopy, FTIR spectroscopy, and thermogravimetric analysis. Horseradish peroxidase (HRP) and lignin peroxidase (LiP) were adsorbed onto magnetite nanoparticles and sol-gel encapsulated in a surface silica layer. Encapsulation enhanced the stability of the biocatalysts over time and thermal stability. The biocatalysts showed appreciable selectivity in oxidation of the organic drinking water pollutants diclofenac, carbamazepine, and paracetamol with improved activity being pharmaceutical specific for each enzyme. In particular, sol-gel encapsulated LiP- and HRP-based nanocomposites were active over 20 consecutive cycles for 20 days at 55 °C (24 h/cycle). The stability of the sol-gel encapsulated catalysts in acidic medium was also improved compared to native enzymes. Carbamazepine and diclofenac were degraded to 68% and 64% by sol-gel LiP composites respectively at pH 5 under elevated temperature. Total destruction of carbamazepine and diclofenac was achieved at pH 3 (55 °C) within 3 days, in the case of both immobilized HRP and LiP. Using NMR spectroscopy, characterization of the drug decomposition products, and decomposition pathways by the peroxidase enzymes suggested.
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Registered trials
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