Evidence map›Paper›PMID 32045675›Full record

ArticleJournal of pain and symptom management2020

Spiritual Care, Pain Reduction, and Preferred Place of Death Among Advanced Cancer Patients in Soweto, South Africa.

Mpho Ratshikana-Moloko, Oluwatosin Ayeni, Jacob M Tsitsi, Michelle L Wong, Judith S Jacobson, Alfred I Neugut, Mfanelo Sobekwa, Maureen Joffe, Keletso Mmoledi, Charmaine L Blanchard and 6 more

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Journal of pain and symptom management, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05587517 (A Clinical Trial of Interventions to Support Family Surrogates of Critically Ill Patients), which is not on this map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
2.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05587517 phase2recruitingnot on this mapstarted 2022, after this paper: background citation

A Clinical Trial of Interventions to Support Family Surrogates of Critically Ill Patients

TypeinterventionalSponsorWeill Medical College of Cornell UniversityRan2022 to 2027Enrolled172ConditionsGrief, Trauma, Psychotherapy, Critical CareArmsEMPOWER, Supportive Conversation
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.

  1. Pooled it
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  4. Review
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  7. Observational
  8. Interventions to support spirituality among adults with cancer: a scoping review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  9. Integrating emergency medical services and palliative care: A nominal group technique.African journal of primary health care & family medicine · 2025
    Article
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  12. South African palliative care provider perspectives on emergency medical services in palliative situations.African journal of emergency medicine : Revue africaine de la medecine d'urgence · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 2 countries.

Mpho Ratshikana-MolokoChris Hani Baragwanath Academic Hospital, Johannesburg, South Africa; Centre for Palliative Care, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa; Non Communicable Diseases Research Division, Wits Health Consortium (Pty) Ltd, Johannesburg, South Africa. Electronic address: mpho.ratshikana-moloko@wits.ac.za.
Oluwatosin AyeniNon Communicable Diseases Research Division, Wits Health Consortium (Pty) Ltd, Johannesburg, South Africa; Department of Paediatrics, SAMRC/Wits Developmental Pathways to Health Research Unit, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa.
Jacob M TsitsiChris Hani Baragwanath Academic Hospital, Johannesburg, South Africa; Department of Medicine, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa.
Michelle L WongDepartment of Medicine, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa; Division of Pulmonology, Chris Hani Baragwanath Academic Hospital, Johannesburg, South Africa.
Judith S JacobsonHerbert Irving Comprehensive Cancer Center, College of Physicians and Surgeons, Columbia University, New York, New York, USA; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, USA.
Alfred I NeugutHerbert Irving Comprehensive Cancer Center, College of Physicians and Surgeons, Columbia University, New York, New York, USA; Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York, USA; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, USA.
Mfanelo SobekwaChris Hani Baragwanath Academic Hospital, Johannesburg, South Africa; Centre for Palliative Care, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa; Non Communicable Diseases Research Division, Wits Health Consortium (Pty) Ltd, Johannesburg, South Africa.
Maureen JoffeNon Communicable Diseases Research Division, Wits Health Consortium (Pty) Ltd, Johannesburg, South Africa; Department of Paediatrics, SAMRC/Wits Developmental Pathways to Health Research Unit, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa; South Africa Medical Research Council Common Epithelial Cancers Research Centre, University of Witwatersrand, Johannesburg, Gauteng, South Africa.
Keletso MmolediChris Hani Baragwanath Academic Hospital, Johannesburg, South Africa; Centre for Palliative Care, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa; Non Communicable Diseases Research Division, Wits Health Consortium (Pty) Ltd, Johannesburg, South Africa.
Charmaine L BlanchardCentre for Palliative Care, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa; Non Communicable Diseases Research Division, Wits Health Consortium (Pty) Ltd, Johannesburg, South Africa.
Witness MapangaNon Communicable Diseases Research Division, Wits Health Consortium (Pty) Ltd, Johannesburg, South Africa.
Paul RuffNon Communicable Diseases Research Division, Wits Health Consortium (Pty) Ltd, Johannesburg, South Africa; Department of Medicine, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa; South Africa Medical Research Council Common Epithelial Cancers Research Centre, University of Witwatersrand, Johannesburg, Gauteng, South Africa; Division of Medical Oncology, Department of Internal Medicine, University of the Witwatersrand Faculty of Health Sciences, Johannesburg, South Africa.
Herbert CubaschSouth Africa Medical Research Council Common Epithelial Cancers Research Centre, University of Witwatersrand, Johannesburg, Gauteng, South Africa; Department of Surgery, Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa.
Daniel S O'NeilSylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, USA.
Tracy A BalboniDana-Farber/Brigham and Women's Cancer Center, Harvard Medical School, Boston, Massachusetts, USA.
Holly G PrigersonCornell Center for Research on End-of-Life Care, Weill Cornell Medicine, New York, New York, USA.
University of the Witwatersrand · ZASouth African Medical Research Council · ZAColumbia University · USAfrica Health Research Institute · ZACornell University · USHarvard University · USUniversity of Miami · US

Funding

Tumor Biology and Microenvironment ProgramP30CA013696 · NCI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI Anil K Rustgi · 1985 to 2026
$115.3M
Psychosocial Approaches to Better Understanding & End-Stage Cancer Care (PROTECT)R35CA197730 · NCI · WEILL MEDICAL COLL OF CORNELL UNIV · PI Holly Gwen Prigerson · 2015 to 2026
$11.2M
Quality of Death: Ethnic and Psychosocial InfluencesR01CA106370 · NCI · YALE UNIVERSITY · PI PRIGERSON, HOLLY GWEN · 2004 to 2015
$4.1M
HIV's Effects on Breast Cancer Treatment and Outcomes in South AfricaR01CA192627 · NCI · WITS HEALTH CONSORTIUM (PTY), LTD · PI JACOBSON, JUDITH S, JOFFE, MAUREEN · 2015 to 2019
$1.7M
NCI NIH HHS P30 CA013696NCI NIH HHS R01 CA106370NCI NIH HHS R01 CA192627NCI NIH HHS R35 CA197730
6 · The paper itself

Abstract

contextWhen religious and spiritual (R/S) care needs of patients with advanced disease are met, their quality of life (QoL) improves. We studied the association between R/S support and QoL of patients with cancer at the end of life in Soweto, South Africa.

objectivesTo identify R/S needs among patients with advanced cancer receiving palliative care services and to assess associations of receipt of R/S care with patient QoL and place of death.

methodsA prospective cohort study conducted from May 1, 2016 to April 30, 2018 at a tertiary hospital in Soweto, South Africa. Nurses enrolled patients with advanced cancer and referred them to the palliative care multidisciplinary team. Spiritual counselors assessed and provided spiritual care to patients. We compared sociodemographic, clinical, and R/S factors and QoL of R/S care recipients and others.

resultsOf 233 deceased participants, 92 (39.5%) had received R/S care. Patients who received R/S care reported less pain (2.82 ± 1.23 vs. 1.93 ± 1.69), used less morphine, and were more likely to die at home than patients who did not (57.5% compared with 33.7%). On multivariate logistic regression analysis, adjusting for significant confounding influences and baseline African Palliative Care Association Palliative care Outcome Scale scores, receipt of spiritual care was associated with reduced pain and family worry (odds ratio 0.33; 95% CI 0.11-0.95 and odds ratio 3.43; 95% CI 1.10-10.70, respectively).

conclusionPatients with cancer have R/S needs. R/S care among our patients appeared to improve their end-of-life experience. More research is needed to determine the mechanisms by which R/S care may have improved the observed patient outcomes.

Indexed as

NeoplasmsTerminal CareHumansPainPalliative CareProspective StudiesQuality of LifeSouth AfricaSpiritualitycancer patientspainpalliative careplace of deathReligionspirituality

Identifiers

PMID32045675
PMCPMC7311268
OpenAlexW3004442632

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.