Evidence map›Paper›PMID 32045545›Full record

ArticleJCO global oncology2020

Attributable Causes of Cancer in Vietnam.

Thuy Phuong Nguyen, Hung N Luu, Mai Vu Tuyet Nguyen, Mo Thi Tran, Thuy Thi Van Tuong, Chi Thi Du Tran, Paolo Boffetta

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in JCO global oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06681636 (A Non-inferiority Study Comparing the Immunogenicity of a Standard or an Extended Three-dose Nonavalent Human Papillomavirus Vaccine Schedule Between High-risk Women Aged 18-26 Years and Age-matched Women in the General Population), which is not on this map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
1.5field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06681636 phase2not yet recruitingnot on this mapstarted 2024, after this paper: background citation

A Non-inferiority Study Comparing the Immunogenicity of a Standard or an Extended Three-dose Nonavalent Human Papillomavirus Vaccine Schedule Between High-risk Women Aged 18-26 Years and Age-matched Women in the General Population

TypeinterventionalSponsorNational Institute of Hygiene and Epidemiology, VietnamRan2024 to 2027Enrolled300ConditionsHPV Infection, Cervical Cancer, Anogenital Cancer, Anogenital WartsArmsHuman papillomavirus 9-valent vaccine, Recombinant
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.

  1. Pooled it
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  7. Cancer Burden Across The South East Asia Nation (ASEAN) in 2022.Asian Pacific journal of cancer prevention : APJCP · 2025
    Article
  8. Article
  9. Article
  10. Review
  11. Association between Sleep Duration and Colorectal Adenomas: Findings from a Case-Control Study in Vietnam.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Thuy Phuong NguyenMenzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia.
Hung N LuuDivision of Cancer Control and Population Sciences, University of Pittsburgh Medical Center Hillman Cancer Center, University of Pittsburgh, Pittsburgh, PA.
Mai Vu Tuyet NguyenVietnam Colorectal Cancer and Polyps Study, Vinmec Healthcare System, Hanoi, Vietnam.
Mo Thi TranVietnam Colorectal Cancer and Polyps Study, Vinmec Healthcare System, Hanoi, Vietnam.
Thuy Thi Van TuongVietnam Colorectal Cancer and Polyps Study, Vinmec Healthcare System, Hanoi, Vietnam.
Chi Thi Du TranVietnam Colorectal Cancer and Polyps Study, Vinmec Healthcare System, Hanoi, Vietnam.
Paolo BoffettaTisch Cancer Center, Icahn School of Medicine at Mount Sinai, New York, NY.
Icahn School of Medicine at Mount Sinai · USUniversity of Tasmania · AUUPMC Hillman Cancer Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeVietnam is undergoing rapid socio-economic transition with an increasing cancer burden. The contribution of modifiable risk factors to cancers in Vietnam has not been studied. Therefore, we sought to evaluate the attributable causes of cancer in Vietnam.

methodsWe reviewed the data on burden of cancer in Vietnam from 2 cancer registries in Hanoi and Ho Chi Minh City between 1995 and 2012. Next, we calculated the fractions of cancers occurring in 2018 attributable to established modifiable risk factors whose impact could be quantified. Data on exposure prevalence were obtained for the period from 2000 to 2010 from national sources wherever possible.

resultsCancer incidence in Vietnam has decreased slightly in both sexes. Cancer related to infectious agents decreased sharply, whereas cancer related to nutrition and metabolism has increased. In 2018, established carcinogens included in the analysis explained 47.0% of cancer burden in Vietnam. Chronic infections accounted for 29.1% of cancers (34.7% in men and 22.1% in women), tobacco smoking for 13.5% (23.9% in men and 0.8% in women), and alcohol drinking for 10.3%. Passive smoking was responsible for 8.8% of cancers in women. Other risk factors, including overweight or obesity, nulliparity, and low vegetable and fruit intake, accounted for < 1% of all cancers each.

conclusionCancer incidence is slowly decreasing in Vietnam, and the causes of more than half of cancers remain unexplained. This result underlines the need for further epidemiologic and fundamental research. Our findings confirm the notion that controlling oncogenic infections and decreasing tobacco smoking are the most effective approaches to reduce the burden of cancer in Vietnam, but other risk factors, including alcohol drinking and diet, should not be neglected.

Indexed as

NeoplasmsCitiesFemaleHumansIncidenceMaleVietnam

Identifiers

PMID32045545
PMCPMC7051248
OpenAlexW3005963831

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.