Evidence map›Paper›PMID 32045358›Full record

ArticleEndocrine connections2020

Mindfulness affects stress, ghrelin, and BMI of obese children: a clinical trial.

Mardia López-Alarcón, Jessie N Zurita-Cruz, Alonso Torres-Rodríguez, Karla Bedia-Mejía, Manuel Pérez-Güemez, Leonel Jaramillo-Villanueva, Mario E Rendón-Macías, Jose R Fernández, Patricia Martínez-Maroñas

Open access · goldAbstract read
In one paragraph

Article in Endocrine connections, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 4 pooled it
1.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 4 syntheses or guidelines pooled it, 26 citations in OpenAlex.

  1. Pooled it
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  3. Weight-neutral interventions in young people with high body mass index: A systematic review.Nutrition & dietetics : the journal of the Dietitians Association of Australia · 2023
    Pooled it
  4. Pooled it
  5. Trial
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  11. [The Medical Nutrition Research Unit: towards the new challenges of translational research].Revista medica del Instituto Mexicano del Seguro Social · 2025
    Article
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  15. Evidence Base Update on Behavioral Treatments for Overweight and Obesity in Children and Adolescents.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53 · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Mardia López-AlarcónUnidad de Investigación Médica en Nutrición, Hospital de Pediatría, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, México, Mexico.
Jessie N Zurita-CruzUnidad de Investigación Médica en Nutrición, Hospital de Pediatría, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, México, Mexico.
Alonso Torres-RodríguezEscuela Española de Desarrollo Transpersonal, Madrid, España.
Karla Bedia-MejíaUnidad de Investigación Médica en Nutrición, Hospital de Pediatría, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, México, Mexico.
Manuel Pérez-GüemezUnidad de Investigación Médica en Nutrición, Hospital de Pediatría, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, México, Mexico.
Leonel Jaramillo-VillanuevaDepartamento de Psiquiatría, Hospital de Pediatría, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, México, Mexico.
Mario E Rendón-MacíasUniversidad Panamericana, Facultad de Ciencias de la Salud, Escuela de Medicina, México, Mexico.
Jose R FernándezDepartments of Nutrition Sciences and Biostatistics, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Patricia Martínez-MaroñasEscuela Española de Desarrollo Transpersonal, Madrid, España.
Centro Medico Nacional Siglo XXI · MXMexican Social Security Institute · MXUniversidad Panamericana · MXUniversity of Alabama at Birmingham · US

Funding

Why is the prevalence of obesity so high in U.S. Southern States? Regional predictors of BMI and obesity treatment response.P30DK056336 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BARBARA A GOWER · 2000 to 2026
$31.9M
NIDDK NIH HHS P30 DK056336
6 · The paper itself

Abstract

Childhood obesity is associated with stress. However, most treatment strategies include only dietary and physical activity approaches. Mindfulness may assist in weight reduction, but its effectiveness is unclear. We assessed the effect of mindfulness on stress, appetite regulators, and weight of children with obesity and anxiety. A clinical study was conducted in a pediatric hospital. Eligible children were 10-14 years old, BMI ≥95th percentile, Spence anxiety score ≥55, and who were not taking any medication or supplementation. Participants were assigned to receive an 8-week conventional nutritional intervention (CNI) or an 8-week mindfulness-based intervention plus CNI (MND-CNI). Anthropometry, body composition, leptin, insulin, ghrelin, cortisol, and Spence scores were measured at baseline and at the end of the intervention. Anthropometry was analyzed again 8 weeks after concluding interventions. Log-transformed and delta values were calculated for analysis. Thirty-three MND-CNI and 12 CNI children finished interventions; 17 MND-CNI children accomplished 16 weeks. At the end of the intervention, significant reductions in anxiety score (-6.21 ± 1.10), BMI (-0.45 ± 1.2 kg/m2), body fat (-1.28 ± 0.25%), ghrelin (-0.71 ± 0.37 pg/mL), and serum cortisol (-1.42 ± 0.94 µg/dL) were observed in MND-CNI children. Changes in anxiety score, ghrelin, and cortisol were different between groups (P < 0.05). Children who completed 16 weeks decreased BMI after intervention (-0.944 ± 0.20 kg/m2, P < 0.001) and remained lower 8 weeks later (-0.706 ± 0.19 kg/m2, P = 0.001). We concluded that mindfulness is a promising tool as an adjunctive therapy for childhood obesity. However, our findings need confirmation in a larger sample population.

Indexed as

childrencortisolghrelinmindfulnessobesitystress

Identifiers

PMID32045358
PMCPMC7040861
OpenAlexW3004629579

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.