Evidence map›Paper›PMID 32044394›Full record

ArticleAnaerobe2020

Glutathione catabolism by Treponema denticola impacts its pathogenic potential.

Lianrui Chu, Yimin Wu, Xiaoping Xu, Linda Phillips, David Kolodrubetz

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Anaerobe, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Lianrui ChuDepartment of Developmental Dentistry, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
Yimin WuDepartment of Developmental Dentistry, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
Xiaoping XuDepartment of Periodontics, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
Linda PhillipsDepartment of Microbiology, Immunology and Molecular Genetics, UT Health San Antonio, 7703 Floyd Curl Drive, San Antonio, TX, 78229, USA.
David KolodrubetzDepartment of Microbiology, Immunology and Molecular Genetics, UT Health San Antonio, 7703 Floyd Curl Drive, San Antonio, TX, 78229, USA. Electronic address: kolodrubetz@uthscsa.edu.
The University of Texas Health Science Center at San Antonio · US

Funding

Multiple Functions of Glutathione Catabolism and H2S in T. denticola PathogenesisR01DE023532 · NIDCR · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI CHU, LIANRUI · 2014 to 2016
$1.1M
NIDCR NIH HHS R01 DE023532
6 · The paper itself

Abstract

Treponema denticola is a spirochete that is etiologic for periodontal diseases. This bacterium is one of two periodontal pathogens that have been shown to have a complete three step enzymatic pathway (GTSP) that catabolizes glutathione to H

Indexed as

BiomarkersFibroblastsGenes, BacterialGlutathioneGram-Negative Bacterial InfectionsHemolysisHumansMutationTreponema denticolaVirulenceBiomarkersGlutathioneggt mutantGingival fibroblast deathGlutathione catabolismPeriodontal diseaseTreponema denticola

Identifiers

PMID32044394
PMCPMC7153967
OpenAlexW3004538887

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.