Evidence map›Paper›PMID 32044154›Full record

ReviewAntiviral research2020

Prevention and treatment of neonatal herpes simplex virus infection.

Nicole L Samies, Scott H James

Open access · greenAbstract readReview
In one paragraph

Review in Antiviral research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. A comprehensive method for quantifying human cytomegalovirus plaque assays.Frontiers in cellular and infection microbiology · 2026
    Article
  7. The Placenta as an Immunological Environment.British journal of biomedical science · 2025
    Review
  8. Disseminated herpes simplex virus infection in pregnancyBiomedica : revista del Instituto Nacional de Salud · 2024
    Article
  9. Article
  10. Genomoviruses in Liver Samples ofMicroorganisms · 2024
    Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Nicole L SamiesDepartment of Pediatrics, Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, AL, USA.
Scott H JamesDepartment of Pediatrics, Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, AL, USA. Electronic address: sjames@peds.uab.edu.
University of Alabama at Birmingham · US

Funding

Emerging Antiviral Resistance in Congenital Cytomegalovirus InfectionK08AI108691 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI JAMES, SCOTT H · 2014 to 2018
$807k
NIAID NIH HHS K08 AI108691
6 · The paper itself

Abstract

Herpes simplex virus (HSV), a member of the Herpesviridae family, is a well-known cause of infections including genital herpes and herpes labialis in the adolescent and adult population. Transmission of HSV infection to an infant during the first 4-6 weeks of life can lead to devastating disease with the potential for poor outcomes. Early diagnosis is imperative when evaluating neonatal HSV infection in order to prevent further disease progression, neurological complications, and even death. In the past 4 decades, significant advancements have been made in the diagnosis, treatment, and prevention of neonatal HSV infection, but there remains room for improvement as efforts continue to reduce the burden of disease caused by this infection.

Indexed as

AcyclovirAntiviral AgentsFemaleHerpes GenitalisHerpes SimplexHumansInfectious Disease Transmission, VerticalPregnancyPregnancy Complications, InfectiousAcyclovirAntiviral AgentsAcyclovirAntiviral therapyHerpes simplex virusMother-to-child transmissionNeonatal herpes

Identifiers

PMID32044154
PMCPMC8713303
OpenAlexW3004716083

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.