Evidence map›Paper›PMID 32044090›Full record

ArticleFertility and sterility2020

Influence of subfertility and assisted reproductive technology treatment on mortality of women after delivery.

Charles C Coddington, Daksha Gopal, Xiaohui Cui, Howard Cabral, Hafsatou Diop, Judy E Stern

Open access · greenAbstract read
In one paragraph

Article in Fertility and sterility, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Charles C CoddingtonDepartment of Reproductive Endocrinology and Infertility, Mayo Clinic, Rochester, Minnesota; Atrium Health, Charlotte, North Carolina. Electronic address: Charles.coddington@atriumhealth.org.
Daksha GopalBiostatistics, Boston University SPH, Boston, Massachusetts.
Xiaohui CuiMass Department of Public Health, Boston, Massachusetts.
Howard CabralBiostatistics, Boston University SPH, Boston, Massachusetts.
Hafsatou DiopMass Department of Public Health, Boston, Massachusetts.
Judy E SternDepartment of Obstetrics and Gynecology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire.
Massachusetts Department of Public Health · USDartmouth–Hitchcock Medical Center · USMayo Clinic · US

Funding

Women's Health After Assisted Reproductive Technology: A Population-Based StudyR01HD067270 · NICHD · DARTMOUTH-HITCHCOCK CLINIC · PI DIOP, HAFSATOU, STERN, JUDY E · 2011 to 2020
$7.4M
NICHD NIH HHS R01 HD067270
6 · The paper itself

Abstract

objectiveTo compare incidence, risk factors, and etiology of women's deaths in fertile, subfertile, and undergoing assisted reproductive technology (ART) in the years after delivery.

designRetrospective cohort.

settingUniversity hospital. PATIENT(S): Women who had delivered in Massachusetts. INTERVENTION(S): This study used data from the Society for Assisted Reproductive Technology Clinic Outcome Reporting System linked to vital records, hospital stays, and the Massachusetts death file. Mortality of patients delivered from 2004-2013 was evaluated through 2015. The exposure groups, determined on the basis of the last delivery, were ART-treated (linked to Society for Assisted Reproductive Technology Clinic Outcome Reporting System), subfertile (no ART but with indicators of subfertility including birth certificate checkbox for fertility treatment, prior hospitalization for infertility [International Classification of Disease codes 9 628 or V23], and/or prior delivery with checkbox or ART), or fertile (neither ART nor subfertile). Numbers (per 100,000 women-years) and causes of death were obtained from the Massachusetts death file. MAIN OUTCOME MEASURE(S): Mortality of women after delivery in each of the three fertility groups and the most common etiology of death in each. RESULT(S): We included 483,547 women: 16,429 ART, 11,696 subfertile, and 455,422 fertile among whom there were 1,280 deaths with 21.1, 25.5, and 44.7 deaths, respectively, per 100,000 women-years. External causes (violence, accidents, and poisonings) were the most common reasons for death in the fertile group. Deaths occurred on average 46 months after delivery. When external causes of death were removed, there were 19.1, 17.0, and 25.6 deaths per 100,000 women-years and leading causes of death in all groups were cancer and circulatory problems. CONCLUSION(S): The study presents reassuring data that death rates within 5 years of delivery in ART-treated and subfertile women do not differ from those in fertile women.

Indexed as

Delivery, ObstetricMaternal MortalityReproductive Techniques, AssistedAdultCohort StudiesFemaleHumansInfertilityInfertility, FemaleMassachusettsMaternal AgeMiddle AgedPregnancyRetrospective StudiesTime FactorsTreatment Outcomeassisted reproductionfertilityIVFMortalitysubfertile

Identifiers

PMID32044090
PMCPMC7088468
OpenAlexW3004566481

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.