Evidence map›Paper›PMID 32043973›Full record

ArticleeLife2020

Postural control of arm and fingers through integration of movement commands.

Scott T Albert, Alkis M Hadjiosif, Jihoon Jang, Andrew J Zimnik, Demetris S Soteropoulos, Stuart N Baker, Mark M Churchland, John W Krakauer, Reza Shadmehr

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 58 citations in OpenAlex.

  1. Article
  2. Article
  3. A Spinal Origin for the Obligate Flexor Synergy in the Nonhuman Primate: Implications for Control of Reaching.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
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  7. Identifying Distinct Neural Features between the Initial and Corrective Phases of Precise Reaching Using AutoLFADS.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  8. Preparatory activity and the expansive null-space.Nature reviews. Neuroscience · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. Neuromuscular control: from a biomechanist's perspective.Frontiers in sports and active living · 2023
    Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Scott T AlbertDepartment of Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, United States.ORCID 0000-0001-9140-1077
Alkis M HadjiosifDepartment of Neurology, Johns Hopkins School of Medicine, Baltimore, United States.ORCID 0000-0001-8823-3631
Jihoon JangDepartment of Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, United States.
Andrew J ZimnikDepartment of Neuroscience, Columbia University, New York, United States.
Demetris S SoteropoulosInstitute of Neuroscience, Newcastle University, Newcastle upon Tyne, United Kingdom.
Stuart N BakerInstitute of Neuroscience, Newcastle University, Newcastle upon Tyne, United Kingdom.
Mark M ChurchlandDepartment of Neuroscience, Columbia University, New York, United States.ORCID 0000-0001-9123-6526
John W KrakauerDepartment of Neurology, Johns Hopkins School of Medicine, Baltimore, United States.ORCID 0000-0002-4316-1846
Reza ShadmehrDepartment of Biomedical Engineering, Johns Hopkins School of Medicine, Baltimore, United States.ORCID 0000-0002-7686-2569
Johns Hopkins University · USColumbia University · USNewcastle University · GB

Funding

Modeling multi-area dynamics during motor controlU19NS104649 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI COSTA, RUI M. · 2017 to 2021
$15.3M
Instrumentation, Fabrication, and Design CoreP30EY019007 · NEI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Xin Zhang · 2010 to 2026
$12.9M
The multiple components of motor memoryR01NS078311 · NINDS · JOHNS HOPKINS UNIVERSITY · PI SHADMEHR, REZA · 2012 to 2021
$3.8M
A dynamical systems approach to fundamental questions in neuroscienceDP2NS083037 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CHURCHLAND, MARK M · 2012 to 2014
$2.6M
CRCNS: Understanding flexible neural computations in the motor cortexR01NS100066 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CUNNINGHAM, JOHN PATRICK · 2016 to 2018
$937k
The feedback response to error as a teaching signal for motor learningF31NS095706 · NINDS · JOHNS HOPKINS UNIVERSITY · PI ALBERT, SCOTT TYLER · 2015 to 2018
$132k
The neural workings of self-initiated and quasi-automatic movementsF32NS092350 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LARA, ANTONIO HOMERO · 2015 to 2016
$79k
Medical Research Council MR/K023012/1Medical Research Council MR/P023967Medical Research Council MR/P023967/1NEI NIH HHS P30 EY019007NINDS NIH HHS 1DP2NS083037NINDS NIH HHS 1U19NS104649NINDS NIH HHS DP2 NS083037NINDS NIH HHS F31 NS095706NINDS NIH HHS F31NS095706NINDS NIH HHS F32 NS092350NINDS NIH HHS F32NS092350NINDS NIH HHS R01 NS078311NINDS NIH HHS R01NS078311NINDS NIH HHS R01 NS100066NINDS NIH HHS R01NS100066NINDS NIH HHS U19 NS104649
6 · The paper itself

Abstract

Every movement ends in a period of stillness. Current models assume that commands that hold the limb at a target location do not depend on the commands that moved the limb to that location. Here, we report a surprising relationship between movement and posture in primates: on a within-trial basis, the commands that hold the arm and finger at a target location depend on the mathematical integration of the commands that moved the limb to that location. Following damage to the corticospinal tract, both the move and hold period commands become more variable. However, the hold period commands retain their dependence on the integral of the move period commands. Thus, our data suggest that the postural controller possesses a feedforward module that uses move commands to calculate a component of hold commands. This computation may arise within an unknown subcortical system that integrates cortical commands to stabilize limb posture.

Indexed as

Models, NeurologicalMovementAdaptation, PhysiologicalAnimalsCase-Control StudiesFingersHaplorhiniHumansPostural BalancePyramidal TractsStrokehumanintegrationmotor controlmotor learningneurosciencepostureReachingrhesus macaquestroke

Identifiers

PMID32043973
PMCPMC7062460
OpenAlexW3005938108

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.