Evidence map›Paper›PMID 32043969›Full record

ArticleeLife2020

Etv transcription factors functionally diverge from their upstream FGF signaling in lens development.

Ankur Garg, Abdul Hannan, Qian Wang, Neoklis Makrides, Jian Zhong, Hongge Li, Sungtae Yoon, Yingyu Mao, Xin Zhang

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ankur Garg *Department of Ophthalmology, Columbia University, New York, United States.
Abdul Hannan *Department of Ophthalmology, Columbia University, New York, United States.
Qian Wang *Department of Ophthalmology, Columbia University, New York, United States.
Neoklis MakridesDepartment of Ophthalmology, Columbia University, New York, United States.
Jian ZhongBurke Neurological Institute and Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, White Plains, United States.
Hongge LiDepartment of Ophthalmology, Columbia University, New York, United States.
Sungtae YoonDepartment of Ophthalmology, Columbia University, New York, United States.
Yingyu MaoDepartment of Ophthalmology, Columbia University, New York, United States.
Xin ZhangDepartment of Ophthalmology, Columbia University, New York, United States.ORCID 0000-0001-5555-0825
Columbia University · USCornell University · US

Funding

Instrumentation, Fabrication, and Design CoreP30EY019007 · NEI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Xin Zhang · 2010 to 2026
$12.9M
Signaling Mechanisms of Lens DevelopmentR01EY017061 · NEI · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI ZHANG, XIN · 2006 to 2025
$9.0M
PDGF signaling in lens developmentR01EY025933 · NEI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ZHANG, XIN · 2015 to 2023
$3.2M
NEI NIH HHS EY017061NEI NIH HHS EY025933NEI NIH HHS P30 EY019007NEI NIH HHS R01 EY017061NEI NIH HHS R01 EY025933
6 · The paper itself

Abstract

The signal regulated transcription factors (SRTFs) control the ultimate transcriptional output of signaling pathways. Here, we examined a family of FGF-induced SRTFs -

Indexed as

Cell DifferentiationAnimalsCrystallinsDNA-Binding ProteinsEpithelial CellsJagged-1 ProteinLens, CrystallineMAP Kinase Signaling SystemMiceProto-Oncogene Proteins c-mafReceptors, Fibroblast Growth FactorReceptors, NotchTOR Serine-Threonine KinasesTranscription FactorsCrystallinsDNA-Binding ProteinsEtv1 protein, mouseJag1 protein, mouseJagged-1 ProteinMaf protein, mousemTOR protein, mouseProto-Oncogene Proteins c-mafReceptors, Fibroblast Growth FactorReceptors, NotchTOR Serine-Threonine KinasesTranscription Factorsdevelopmental biologyETSFGFlens developmentmousemTORNotchPEA3

Identifiers

PMID32043969
PMCPMC7069720
OpenAlexW3005884328

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.