ArticleESC heart failure2020
Early cardiac unloading with ImpellaCP™ in acute myocardial infarction with ventricular septal defect.
Article in ESC heart failure, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- ECMO and Impella Support Strategies as a Bridge to Surgical Repair of Post-Infarction Ventricular Septal Rupture.Medicina (Kaunas, Lithuania) · 2022Pooled it
- Perioperative management of postinfarction ventricular septal rupture: a comparison of Impella with intra-aortic balloon pump.Heart and vessels · 2025Article
- The role of Impella in the pre-procedural management of post-infarct ventricular septal defect: a systematic review.Interdisciplinary cardiovascular and thoracic surgery · 2024Article
- Left ventricular perforation by Impella 5.5 during surgery for postinfarction ventricular septal rupture.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2024Article
- Echocardiographic Detection of an Undiagnosed Ventricular Septal Defect Hidden Behind a Postinfarction Ventricular Septal Rupture.CASE (Philadelphia, Pa.) · 2024Article
- Preoperative Impella therapy in patients with ventricular septal rupture and cardiogenic shock: haemodynamic and organ function outcomes.Interdisciplinary cardiovascular and thoracic surgery · 2024Article
- Delayed surgical repair via right ventricular approach with Impella and extracorporeal life support in post-myocardial infarction ventricular septal defect: A case report.International journal of surgery case reports · 2024Article
- Successful use of left ventricular support device (Impella 5.0) and extracorporeal membrane oxygenation (ECMO) for postoperative cardiac arrest after lung cancer surgery: a case report.Journal of surgical case reports · 2023Article
- Improving Survival in Cardiogenic Shock-A Propensity Score-Matched Analysis of the Impact of an Institutional Allocation Protocol to Short-Term Mechanical Circulatory Support.Life (Basel, Switzerland) · 2022Article
- Optimized patient selection in high-risk protected percutaneous coronary intervention.European heart journal supplements : journal of the European Society of Cardiology · 2022Article
- A new dimension to the STEMI-related mortality risk seen in the COVID-19 pandemic era.The American journal of emergency medicine · 2022Article
- Triple patch technique to repair ventricular septal rupture.Annals of cardiothoracic surgery · 2022Review
- Pre- and post-operative mechanical circulatory support in surgical repair of post-acute myocardial infarction mechanical complications.Annals of cardiothoracic surgery · 2022Review
- Impella 5.0 support before, during, and after surgical ventriculoplasty following acute myocardial infarction in the COVID-19 era: a case report.European heart journal. Case reports · 2021Article
- The Ongoing - and Resurgent - Challenge of Post-Infarct Ventricular Septal Defect Management.Cardiovascular revascularization medicine : including molecular interventions · 2020Article
- Early cardiac unloading with ImpellaCP™ in acute myocardial infarction with ventricular septal defect.ESC heart failure · 2020Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite a relative contraindication, mechanical support with Impella™ left ventricular assist device has already been described for ischaemic ventricular septal defect treatment, either as a bridge to surgery, as intraoperative mechanical haemodynamic support, or to ensure intraprocedural haemodynamic stability during device closure. We describe two cases of ventricular septal defect complicating acute myocardial infarction, where the percutaneous ImpellaCP was implanted early (differently than previously described) with the aim of preventing haemodynamic instability, while deferring surgical repair. We present a report of haemodynamic, echocardiographic, biochemical, and clinical data of two consecutive cases of ImpellaCP use, within a minimally invasive monitoring and therapeutic approach. In two cases of subacute myocardial infarction-related ventricular septal defect not amenable to percutaneous device closure, the use ImpellaCP was successful: it was followed by effective and rapid right and left ventricular unloading, by major haemodynamic instability prevention and protection from systemic venous congestion, from kidney and splanchnic organ failures. This allowed bridging to appropriately timed surgical repair. These cases suggest a potentially effective, clinically grounded strategy in the early management of ischaemic ventricular septal defect patients, with the aim of deferring surgery beyond the safer 7 days cutoff associated with a lower perioperative mortality.
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