Evidence map›Paper›PMID 32043446›Full record

ArticleThe American journal of tropical medicine and hygiene2020

The Prevalence and Outcomes of Sepsis in Adult Patients in Two Hospitals in Malawi.

Raphael Kazidule Kayambankadzanja, Carl Otto Schell, Felix Namboya, Tamara Phiri, Grace Banda-Katha, Samson Kwazizira Mndolo, Andy Bauleni, Markus Castegren, Tim Baker

Open access · bronzeAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 3 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 3 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
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  8. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Raphael Kazidule KayambankadzanjaCollege of Medicine, University of Malawi, Blantyre, Malawi.
Carl Otto SchellDepartment of Internal Medicine, Nyköping Hospital, Nyköping, Sweden.
Felix NamboyaCollege of Medicine, University of Malawi, Blantyre, Malawi.
Tamara PhiriDepartment of Internal Medicine, Queen Elizabeth Central Hospital, Blantyre, Malawi.
Grace Banda-KathaDepartment of Emergency Medicine, College of Medicine, University of Malawi, Blantyre, Malawi.
Samson Kwazizira MndoloDepartment of Anaesthesia and Intensive Care, Queen Elizabeth Central Hospital, Blantyre, Malawi.
Andy BauleniMalaria Alert Centre, College of Medicine, Blantyre, Malawi.
Markus CastegrenPerioperative Medicine & Intensive Care, Karolinska University Hospital, Stockholm, Sweden.
Tim BakerDepartment of Anaesthesia and Intensive Care, Queen Elizabeth Central Hospital, Blantyre, Malawi.
University of Malawi · MWQueen Elizabeth Central Hospital · MWKarolinska Institutet · SEKarolinska University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There are an estimated 19.4 million sepsis cases every year, many of them in low-income countries. The newly adopted definition of sepsis uses Sequential Organ Failure Assessment Score (SOFA), a score which is not feasible in many low-resource settings. A simpler quick-SOFA (qSOFA) based solely on vital signs score has been devised for identification of suspected sepsis. This study aimed to determine in-hospital prevalence and outcomes of sepsis, as defined as suspected infection and a qSOFA score of 2 or more, in two hospitals in Malawi. The secondary aim was to evaluate qSOFA as a predictor of mortality. A cross-sectional study of adult in-patients in two hospitals in Malawi was conducted using prospectively collected single-day point-prevalence data and in-hospital follow-up. Of 1,135 participants, 81 (7.1%) had sepsis. Septic patients had a higher hospital mortality rate (17.5%) than non-septic infected patients (9.0%,

Indexed as

InpatientsAdolescentAdultAgedAged, 80 and overAnti-Bacterial AgentsBacterial InfectionsFemaleHIV InfectionsHumansMalawiMaleMiddle AgedSepsisTreatment OutcomeYoung AdultAnti-Bacterial Agents

Identifiers

PMID32043446
PMCPMC7124904
OpenAlexW3006294421

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.