ArticleBJPsych open2020
Cognitive decline and mortality in a community-based sample of homeless and precariously housed adults: 9-year prospective study.
Article in BJPsych open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.
- Associations between Homelessness and Alzheimer's Disease and Related Dementia: A Systematic Review.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2022Pooled it
- Long-term trajectories of memory, depression, and mobility independence before death: a multi-cohort study.Translational psychiatry · 2026Article
- Observational
- Cognitive Correlates of Resilience in Adults Experiencing Homelessness.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2025Article
- Dementia care and mortality in people experiencing homelessness: A matched cohort study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- Comparing major comorbidity indices as predictors of all-cause mortality in the Veterans Affairs health care system.Journal of clinical epidemiology · 2025Article
- Adolescent Obesity and Charlson Comorbidity Index in Young Adults.Journal of clinical medicine · 2025Article
- Health Deficits Among People Experiencing Homelessness in an Australian Capital City: An Observational Study.International journal of environmental research and public health · 2025Observational
- Examining the risk of delirium in patients hospitalized with COVID-19: Insights from the homeless population.PloS one · 2025Article
- Memory, fluid reasoning, and functional capacity in adults experiencing homelessness.The Clinical neuropsychologist · 2023Article
- Accelerated aging in people experiencing homelessness: A rapid review of frailty prevalence and determinants.Frontiers in public health · 2023Review
- Article
- Traumatic brain injury in precariously housed persons: Incidence and risks.EClinicalMedicine · 2022Article
- Neurocognitive health of older adults experiencing homelessness in Oakland, California.Frontiers in neurology · 2022Article
- Neurologic Complications of Poverty: the Associations Between Poverty as a Social Determinant of Health and Adverse Neurologic Outcomes.Current neurology and neuroscience reports · 2021Review
- Associations of substance use, psychosis, and mortality among people living in precarious housing or homelessness: A longitudinal, community-based study in Vancouver, Canada.PLoS medicine · 2020Article
- Amygdala Nuclei Volumes Are Selectively Associated With Social Network Size in Homeless and Precariously Housed Persons.Frontiers in behavioral neuroscience · 2020Article
Corrections and comments
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Authors and funding
15 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHomeless and precariously housed individuals experience a high burden of comorbid illnesses, and excess mortality. Cross-sectional studies report a high rate of cognitive impairment. Long-term trajectories have not been well investigated in this group.
aimsTo longitudinally assess risks for premature and/or accelerated cognitive ageing, and the relationship with early mortality in homeless and precariously housed people.
methodThis is a 9-year community-based study of 375 homeless and precariously housed individuals from Vancouver, Canada. Annual cognitive testing assessed verbal learning and memory, and inhibitory control. Linear mixed-effects models examined associations between clinical risk factors (traumatic brain injury, psychotic disorders, viral exposure, alcohol dependence) and cognitive change over 9 years. Cox regression models examined the association between cognition and mortality.
resultsTraumatic brain injury and alcohol dependence were associated with decline in verbal memory. Inhibitory control declined, independent of risk factors and to a greater extent in those who died during the study. Better inhibitory control was associated with a 6.6% lower risk of mortality at study entry, with a 0.3% greater effect for each year of life. For each one-point increase in the Charlson Comorbidity Index score at study entry, the risk of mortality was 9.9% higher, and was consistent across age. Adjusting for comorbidities, inhibitory control remained a significant predictor of mortality.
conclusionsFindings raise the possibility of a premature onset, and accelerated trajectory, of cognitive ageing in this group of homeless and precariously housed people. Traumatic brain injury, alcohol dependence and cognition could be treatment priorities.
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