Evidence map›Paper›PMID 32043169›Full record

ArticlePharmaceutical research2020

Regulation of Lipid Membrane Partitioning of Tamoxifen by Ionic Strength and Cholesterol.

Uyen P N Dao, Quan D Nguyen, Trang T Nguyen

Abstract read
PubMed Publisher
In one paragraph

Article in Pharmaceutical research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Uyen P N DaoSchool of Biotechnology, International University, Block 6, Linh Trung Ward, Thu Duc District, Ho Chi Minh City, Vietnam.
Quan D NguyenFaculty of Chemical Engineering, HCMC University of Technology, 268 Ly Thuong Kiet, District 10, Ho Chi Minh City, Vietnam.
Trang T NguyenSchool of Biotechnology, International University, Block 6, Linh Trung Ward, Thu Duc District, Ho Chi Minh City, Vietnam. nttrang@hcmiu.edu.vn.ORCID http://orcid.org/0000-0002-4362-0061
Vietnam National University Ho Chi Minh City · VN

Funding

Viet Nam National University Ho Chi Minh City C2017-28-02
6 · The paper itself

Abstract

purposeThe purpose of this study was to inspect the interactions between an anti-breast cancer, TAM, with model of lipid membranes composed of either zwitterionic DPPC LUVs or anionic DPPG LUVs and how they depend on ionic strength and cholesterol.

methodsThe K

resultsIncreasing salt concentration produced negligible impact on the partitioning of TAM into DPPC bilayer as its K

conclusionIonic strength and cholesterol play a noteworthy role in regulation of TAM partitioning into lipid membranes as they could obstruct or promote such action.

Indexed as

Osmolar Concentration1,2-DipalmitoylphosphatidylcholineCell MembraneCholesterolMembrane LipidsMolecular StructurePhosphatidylglycerolsTamoxifen1,2-Dipalmitoylphosphatidylcholine1,2-dipalmitoylphosphatidylglycerolCholesterolcolfosceril palmitateMembrane LipidsPhosphatidylglycerolsTamoxifencholesterolDPPCDPPGionic strengthtamoxifen

Identifiers

PMID32043169
OpenAlexW3006598754

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.