Evidence map›Paper›PMID 32042976›Full record

ArticleHeliyon2020

Tracking changes of the parameters of glucose-insulin homeostasis during the course of obesity in B6D2F1 mice.

Sakineh Esmaeili Mohsen Abadi, Ramin Balouchzadeh, Guney Uzun, Hoo Sang Ko, H Felix Lee, Sarah Park, Guim Kwon

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Sakineh Esmaeili Mohsen AbadiSchool of Engineering, Southern Illinois University Edwardsville, Edwardsville, IL, 62026, United States.
Ramin BalouchzadehSchool of Engineering, Southern Illinois University Edwardsville, Edwardsville, IL, 62026, United States.
Guney UzunSchool of Engineering, Southern Illinois University Edwardsville, Edwardsville, IL, 62026, United States.
Hoo Sang KoSchool of Engineering, Southern Illinois University Edwardsville, Edwardsville, IL, 62026, United States.
H Felix LeeSchool of Engineering, Southern Illinois University Edwardsville, Edwardsville, IL, 62026, United States.
Sarah ParkLibrary and Information Services, Southern Illinois University Edwardsville, Edwardsville, IL, 62026, United States.
Guim KwonSchool of Pharmacy, Southern Illinois University Edwardsville, Edwardsville, IL, 62026, United States.
Southern Illinois University Edwardsville · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity is one of the primary causes of type 2 diabetes mellitus (T2DM). To better understand how obesity impairs glucose-insulin homeostasis, we tracked fasting blood glucose and insulin levels and the key components of glucose-insulin homeostasis for 7 months in high fat diet (HFD; 45% fat) fed mice (n = 8). Every 2 weeks we measured body weight, fasting blood glucose and insulin levels, and estimated 5 key rate constants of glucose-insulin homeostasis using the methods established previously (Heliyon 3: e00310, 2017). Mice gained weight steadily, more than doubling their weights after 7 months (23.6 ± 0.5 to 52.3 ± 1.4 g). Fasting (basal) insulin levels were elevated (221.3 ± 16.7 to 1043.1 ± 90.5 pmol l

Indexed as

BiochemistryGlucose-insulin homeostasisHigh fat dietInsulinMathematical modelingObesityRate constantsType 2 diabetes

Identifiers

PMID32042976
PMCPMC7002827
OpenAlexW3003591450

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.