Evidence map›Paper›PMID 32042837›Full record

ReviewEye and vision (London, England)2020

Biomechanical diagnostics of the cornea.

Louise Pellegrino Gomes Esporcatte, Marcella Q Salomão, Bernardo T Lopes, Paolo Vinciguerra, Riccardo Vinciguerra, Cynthia Roberts, Ahmed Elsheikh, Daniel G Dawson, Renato Ambrósio

Open access · diamondAbstract readReview
In one paragraph

Review in Eye and vision (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 4 pooled it
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 4 syntheses or guidelines pooled it, 132 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Corneal biomechanical changes in patients with anterior chamber inflammation: a systematic review and meta-analysis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
    Pooled it
  4. Pooled it
  5. Effects of caffeine intake on the biomechanical properties of the cornea: a placebo-controlled, double-blind, crossover pilot study in low caffeine consumers.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2020
    Trial
  6. Article
  7. Article
  8. Observational
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Linking layered corneal compactness to macroscopic biomechanics:Frontiers in bioengineering and biotechnology · 2026
    Article
  16. Regional corneal biomechanics assessment as a function of age using Strain-Stress Index maps.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025
    Review
  17. Article
  18. Article
  19. Analysis of In Vivo Sclera Impact on the Biomechanics of Myopic Eyes.Translational vision science & technology · 2025
    Article
  20. Article

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 5 countries.

Louise Pellegrino Gomes EsporcatteRio de Janeiro Corneal Tomography and Biomechanics Study Group, Rio de Janeiro, Brazil.
Marcella Q SalomãoRio de Janeiro Corneal Tomography and Biomechanics Study Group, Rio de Janeiro, Brazil.
Bernardo T LopesRio de Janeiro Corneal Tomography and Biomechanics Study Group, Rio de Janeiro, Brazil.
Paolo Vinciguerra8Department of Biomedical Science, Humanitas University, Rozzano, Italy.
Riccardo Vinciguerra7School of Engineering, University of Liverpool, Liverpool, L69 3GH UK.
Cynthia Roberts11Department of Ophthalmology and Visual Science, Department of Biomedical Engineering, The Ohio State University, Columbus, OH USA.
Ahmed Elsheikh7School of Engineering, University of Liverpool, Liverpool, L69 3GH UK.
Daniel G Dawson14The University of Florida Department of Ophthalmology, Gainesville, FL USA.
Renato AmbrósioRio de Janeiro Corneal Tomography and Biomechanics Study Group, Rio de Janeiro, Brazil.ORCID 0000-0001-6919-4606
University of Liverpool · GBHospital São Vicente de Paulo · BRHumanitas University · ITInstituto Benjamin Constant · BRInstituto de Olhos de Goiânia · BRMoorfields Eye Hospital NHS Foundation Trust · GBThe Ohio State University · USUniversity of Florida Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Corneal biomechanics has been a hot topic for research in contemporary ophthalmology due to its prospective applications in diagnosis, management, and treatment of several clinical conditions, including glaucoma, elective keratorefractive surgery, and different corneal diseases. The clinical biomechanical investigation has become of great importance in the setting of refractive surgery to identify patients at higher risk of developing iatrogenic ectasia after laser vision correction. This review discusses the latest developments in the detection of corneal ectatic diseases. These developments should be considered in conjunction with multimodal corneal and refractive imaging, including Placido-disk based corneal topography, Scheimpflug corneal tomography, anterior segment tomography, spectral-domain optical coherence tomography (SD-OCT), very-high-frequency ultrasound (VHF-US), ocular biometry, and ocular wavefront measurements. The ocular response analyzer (ORA) and the Corvis ST are non-contact tonometry systems that provide a clinical corneal biomechanical assessment. More recently, Brillouin optical microscopy has been demonstrated to provide in vivo biomechanical measurements. The integration of tomographic and biomechanical data into artificial intelligence techniques has demonstrated the ability to increase the accuracy to detect ectatic disease and characterize the inherent susceptibility for biomechanical failure and ectasia progression, which is a severe complication after laser vision correction.

Indexed as

Corneal biomechanicsCorneal ectasiaCorneal imaging

Identifiers

PMID32042837
PMCPMC7001259
OpenAlexW3008536181

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.