Evidence map›Paper›PMID 32042803›Full record

ArticleAnnals of translational medicine2019

Cystathionine gamma lyase aggravates orthodontic root resorption in mice.

Caizhu Lu, Liyuan Chen, Yongmei Hua

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of translational medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Caizhu LuDepartment of Orthodontics, School of Stomatology/Shanghai Engineering Research Center of Tooth Restoration and Regeneration, Tongji University, Shanghai 200072, China.
Liyuan ChenDepartment of Orthodontics, School of Stomatology/Shanghai Engineering Research Center of Tooth Restoration and Regeneration, Tongji University, Shanghai 200072, China.
Yongmei HuaDepartment of Orthodontics, School of Stomatology/Shanghai Engineering Research Center of Tooth Restoration and Regeneration, Tongji University, Shanghai 200072, China.
Tongji University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aimed to determine the contribution of cystathionine gamma lyase (CSE) to physiological and orthodontic root resorption in mice.

methodsMice genetically deficient in the CSE (CSE

resultsRoot resorption lacunae (RRL) gradually and significantly increased with age in wild type (WT) and CSE

conclusionsCSE contributes significantly to physiological and orthodontic root resorption.

Indexed as

cystathionine gamma lyase (CSE)orthodontic tooth movement (OTM)receptor activator of nuclear factor kappa-B ligand (RANKL)/osteoprotegerin (OPG)Root resorption

Identifiers

PMID32042803
PMCPMC6989964
OpenAlexW2995455026

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.