Evidence map›Paper›PMID 32042749›Full record

ArticleAnnals of translational medicine2019

Identification of genes and pathways related to atherosclerosis comorbidity and depressive behavior via RNA-seq and bioinformation analysis in ApoE

Junjie Zhou, Chunjie Zhang, Xiaoyun Wu, Qi Xie, Lan Li, Ying Chen, Hongbin Yan, Ping Ren, Xi Huang

Open access · diamondAbstract read
In one paragraph

Article in Annals of translational medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

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  9. Effects of the Lipid Metabolites and the Gut Microbiota in ApoEFrontiers in molecular biosciences · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Junjie ZhouInstitute of TCM-related Comorbid Depression, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Chunjie ZhangInstitute of TCM-related Comorbid Depression, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Xiaoyun WuMedical College, Xiamen University, Xiamen 361102, China.
Qi XieInstitute of TCM-related Comorbid Depression, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Lan LiInstitute of TCM-related Comorbid Depression, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Ying ChenInstitute of TCM-related Comorbid Depression, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Hongbin YanInstitute of TCM-related Comorbid Depression, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Ping RenInstitute of TCM-related Comorbid Depression, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Xi HuangInstitute of TCM-related Comorbid Depression, Nanjing University of Chinese Medicine, Nanjing 210023, China.
Nanjing University of Chinese Medicine · CNXiamen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDepression is an independent risk factor for atherosclerosis (AS), which can increase the risk of death and disability from AS. However, the mechanism of AS comorbidity with depression is complex.

methodsApoE

resultsOur findings showed that compared with C57 mice in the control group, ApoE

conclusionsThese results indicate that when ApoE

Indexed as

ApoEAtherosclerosis (AS)depressionRNA

Identifiers

PMID32042749
PMCPMC6990041
OpenAlexW2992678681

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.