Evidence map›Paper›PMID 32042657›Full record

ArticleOpen veterinary journal2020

The Gly152Val mutation possibly confers resistance to beta-lactam antibiotics in ovine

Sarhan R Sarhan, Hayder O Hashim, Mohammed Baqur S Al-Shuhaib

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open veterinary journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Molecular Characterization ofAdvances in virology · 2025
    Article
  2. Article
  3. Molecular detection and phylogenetic analysis ofNew microbes and new infections · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Sarhan R SarhanDepartment of Pharmacology and Physiology, College of Veterinary Medicine, Wasit University, Wasit, Iraq.
Hayder O HashimDepartment of Clinical Laboratory Sciences, College of Pharmacy, University of Babylon, Iraq.
Mohammed Baqur S Al-ShuhaibDepartment of Animal Production, College of Agriculture, Al-Qasim Green University, Al-Qasim, Babil 51001, Iraq.
Ministry of Higher Education and Scientific Research · IQUniversity of Babylon · IQUniversity of Wasit · IQ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The Aim: This study was conducted to detect the Methods: One genetic locus of 1,967 bp that covered the majority of the coding regions of the Results: In addition to standard microbiological tests, PCR-sequencing reactions and phylogenetic analyses confirmed the identity of the targeted MRSA bacteria. Seven novel missense SNPs, including N57T, N115Y, D120N, D139N, G152V, E189K, and F211V, were observed in the Conclusion: The present report indicated a possible role for the observed deleterious G152V SNP in the reduction of PBP2A binding with beta-lactams, which has led to a remarkable increase in MRSA's resistance to antibiotics.

Indexed as

MutationAnimalsBacterial ProteinsDrug Resistance, BacterialMethicillin-Resistant Staphylococcus aureusPenicillin-Binding ProteinsPolymorphism, GeneticSheepSheep DiseasesStaphylococcal InfectionsBacterial ProteinsmecA protein, Staphylococcus aureusPenicillin-Binding ProteinsInfectionIn silicoMecAMissenseVariations

Identifiers

PMID32042657
PMCPMC6971359
OpenAlexW2997459456

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.