Evidence map›Paper›PMID 32042607›Full record

ArticlePublic health action2019

Integrated and patient-selected care facilitates completion of isoniazid preventive therapy in Eswatini.

L V Adams, T S B Maseko, E A Talbot, S W Grande, M M Mkhontfo, Z Z Simelane, A A Achilla, S M Haumba

Abstract read
In one paragraph

Article in Public health action, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

L V AdamsGeisel School of Medicine at Dartmouth, Hanover, NH, USA.
T S B MasekoUniversity Research Co, Mbabane, Eswatini.
E A TalbotGeisel School of Medicine at Dartmouth, Hanover, NH, USA.
S W GrandeGeisel School of Medicine at Dartmouth, Hanover, NH, USA.
M M MkhontfoUniversity Research Co, Mbabane, Eswatini.
Z Z SimelaneUniversity Research Co, Mbabane, Eswatini.
A A AchillaUniversity Research Co, Mbabane, Eswatini.
S M HaumbaUniversity Research Co, Mbabane, Eswatini.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

settingFive human immunodeficiency virus (HIV) care facilities in Eswatini.

objectiveTo identify critical factors that enabled persons living with HIV to successfully complete a 6-month course of isoniazid preventive therapy (IPT) provided through a choice of facility-based or community-based delivery, coordinated with antiretroviral therapy (ART) refills.

designThis was a mixed methods, retrospective cross-sectional study.

resultsBetween June and October 2017, we interviewed 150 participants who had completed IPT in the previous year. Fourteen participants did not recall being offered a choice, and were excluded from the analysis. Of the remaining 136, 56.6% were female and 64.7% chose facility-based care; the median age was 42.5 years. Most participants reported that having a choice was important to their treatment completion (87.7%) and that linking IPT and ART refills facilitated undergoing IPT (98.5%). Participants were knowledgeable about the benefits of IPT and valued the education received from their providers. Participants also reported a high rate of IPT disclosure (95%) to friends and family members.

conclusionOffering patients a choice of IPT delivery, linking IPT with ART refills, emphasizing patient education and engagement with healthcare workers, and supporting disclosure of IPT are critical factors to enabling IPT completion. These interventions should be incorporated throughout Eswatini and in similar high tuberculosis and HIV burden settings.

Indexed as

HIVIPTtuberculosis

Identifiers

PMID32042607
PMCPMC6945734

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.