ReviewCureus2020
Management of Takotsubo Syndrome: A Comprehensive Review.
Review in Cureus, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
49 citing papers in PubMed, 76 citations in OpenAlex.
- Incidence of ischemic stroke in Takotsubo cardiomyopathy patients: a systematic review and meta-analysis.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2026Review
- Takotsubo Cardiomyopathy and Cardiogenic Shock in a 16-Year-Old With Vaping-Induced Pneumonitis.JACC. Case reports · 2026Article
- The Role of Inflammation in Takotsubo Syndrome: From Pathogenic Pathways To Imaging Insights and Therapeutic Perspectives.Current cardiology reports · 2026Review
- An Integrative Review of the Cardiovascular Disease Spectrum: Integrating Multi-Omics and Artificial Intelligence for Precision Cardiology.Diseases (Basel, Switzerland) · 2026Review
- Takotsubo syndrome with concomitant coronary angioplasty and implantable cardioverter-defibrillator implantation: a case report.The British journal of cardiology · 2026Article
- Takotsubo syndrome triggered by perioperative and post-resuscitation stress: Case report.SAGE open medical case reports · 2026Article
- Intraoperative management of Takotsubo cardiomyopathy secondary to parathyroidectomy in the setting of myocardial bridge: a case report.Annals of medicine and surgery (2012) · 2025Article
- Neurological complications in Takotsubo syndrome: A case of concurrent acute stroke.Global cardiology science & practice · 2025Article
- Takotsubo Cardiomyopathy After Esophageal Surgery in a Patient With Undiagnosed Coronary Artery Disease.Cureus · 2025Article
- Validation of Takotsubo Syndrome Scoring System.Diagnostics (Basel, Switzerland) · 2025Article
- High Profile Transvalvular Pump Assisted Recovery for Takotsubo Cardiomyopathy: A Case Series.Journal of clinical medicine · 2025Article
- Case Report: Takotsubo cardiomyopathy caused by acute surgical pathology against the background of colorectal cancer.Frontiers in cardiovascular medicine · 2025Article
- Article
- Heart meets brain: A 25-year-old with a constellation of neurologic symptoms and heart failure.Annals of clinical and translational neurology · 2024Article
- Article
- Takotsubo pathophysiology and complications: what we know and what we do not know.Heart failure reviews · 2024Review
- Takotsubo Syndrome during Pertuzumab and Trastuzumab Therapy for HER2-Positive Metastatic Breast Cancer.Biomedicines · 2024Article
- An Unlikely Cause of Chest Pain: Recurrent Takotsubo Cardiomyopathy.Journal of community hospital internal medicine perspectives · 2024Article
- Pharmacological Triggers of Takotsubo Cardiomyopathy: An Updated Review of Evidence and Recommendations.Current cardiology reviews · 2024Review
- An uncommon combination: a case report of herpes simplex virus encephalitis induced takotsubo cardiomyopathy.AME case reports · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Takotsubo syndrome (TTS), also known as Takotsubo cardiomyopathy, is a transient left ventricular wall dysfunction that is often triggered by physical or emotional stressors. Although TTS is a rare disease with a prevalence of only 0.5% to 0.9% in the general population, it is often misdiagnosed as acute coronary syndrome. A diagnosis of TTS can be made using Mayo diagnostic criteria. The initial management of TTS includes dual antiplatelet therapy, anticoagulants, beta-blockers, angiotensin-converting enzyme inhibitors or aldosterone receptor blockers, and statins. Treatment is usually provided for up to three months and has a good safety profile. For TTS with complications such as cardiogenic shock, management depends on left ventricular outflow tract obstruction (LVOTO). In patients without LVOTO, inotropic agents can be used to maintain pressure, while inotropic agents are contraindicated in patients with LVOTO. In TTS with thromboembolism, heparin should be started, and patients should be bridged to warfarin for up to three months to prevent systemic emboli. Our comprehensive review discussed the management in detail, derived from the most recent literature from observational studies, systematic review, and meta-analyses.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.