Evidence map›Paper›PMID 32042346›Full record

ArticleTheranostics2020

Multimodal and multiscale optical imaging of nanomedicine delivery across the blood-brain barrier upon sonopermeation.

Jan-Niklas May, Susanne K Golombek, Maike Baues, Anshuman Dasgupta, Natascha Drude, Anne Rix, Dirk Rommel, Saskia von Stillfried, Lia Appold, Robert Pola and 8 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 51 citations in OpenAlex.

  1. Article
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  3. Effect of clinically relevant iron oxide nanoparticles on macrophage polarization, tumor growth and tumor microenvironment modulation.Journal of controlled release : official journal of the Controlled Release Society · 2026
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  11. Transformative Materials for Interfacial Drug Delivery.Advanced healthcare materials · 2023
    Article
  12. Nonspherical ultrasound microbubbles.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  13. Article
  14. Article
  15. Imaging-guided nanomedicine development.Current opinion in chemical biology · 2021
    Review
  16. Article
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 3 countries.

Jan-Niklas MayInstitute for Experimental Molecular Imaging (ExMI), University Clinic and Helmholtz Institute for Biomedical Engineering, RWTH Aachen University, Aachen, Germany.
Susanne K GolombekInstitute for Experimental Molecular Imaging (ExMI), University Clinic and Helmholtz Institute for Biomedical Engineering, RWTH Aachen University, Aachen, Germany.
Maike BauesInstitute for Experimental Molecular Imaging (ExMI), University Clinic and Helmholtz Institute for Biomedical Engineering, RWTH Aachen University, Aachen, Germany.
Anshuman DasguptaInstitute for Experimental Molecular Imaging (ExMI), University Clinic and Helmholtz Institute for Biomedical Engineering, RWTH Aachen University, Aachen, Germany.
Natascha DrudeInstitute for Experimental Molecular Imaging (ExMI), University Clinic and Helmholtz Institute for Biomedical Engineering, RWTH Aachen University, Aachen, Germany.
Anne RixInstitute for Experimental Molecular Imaging (ExMI), University Clinic and Helmholtz Institute for Biomedical Engineering, RWTH Aachen University, Aachen, Germany.
Dirk RommelDWI - Leibniz Institute for Interactive Materials, RWTH Aachen University, Aachen, Germany.
Saskia von StillfriedInstitute of Pathology, University Clinic RWTH Aachen, Aachen, Germany.
Lia AppoldInstitute for Experimental Molecular Imaging (ExMI), University Clinic and Helmholtz Institute for Biomedical Engineering, RWTH Aachen University, Aachen, Germany.
Robert PolaCzech Academy of Sciences, Institute of Macromolecular Chemistry, Prague, Czech Republic.
Michal PecharCzech Academy of Sciences, Institute of Macromolecular Chemistry, Prague, Czech Republic.
Louis van BlooisDepartment of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.
Gert StormDepartment of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.
Alexander J C KuehneDWI - Leibniz Institute for Interactive Materials, RWTH Aachen University, Aachen, Germany.
Felix GremseInstitute for Experimental Molecular Imaging (ExMI), University Clinic and Helmholtz Institute for Biomedical Engineering, RWTH Aachen University, Aachen, Germany.
Benjamin TheekInstitute for Experimental Molecular Imaging (ExMI), University Clinic and Helmholtz Institute for Biomedical Engineering, RWTH Aachen University, Aachen, Germany.
Fabian KiesslingInstitute for Experimental Molecular Imaging (ExMI), University Clinic and Helmholtz Institute for Biomedical Engineering, RWTH Aachen University, Aachen, Germany.
Twan LammersInstitute for Experimental Molecular Imaging (ExMI), University Clinic and Helmholtz Institute for Biomedical Engineering, RWTH Aachen University, Aachen, Germany.
RWTH Aachen University · DECzech Academy of Sciences, Institute of Macromolecular Chemistry · CZFraunhofer Institute for Digital Medicine · DEUtrecht University · NLDWI – Leibniz Institute for Interactive Materials · DEUniversität Ulm · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsBlood-Brain BarrierBrainBrain DiseasesDrug Delivery SystemsFluorescent DyesLiposomesMiceMice, NudeMicrobubblesNanomedicineOptical ImagingUltrasonographyFluorescent DyesLiposomesBlood-brain barrierDrug deliveryMicrobubblesNanomedicineUltrasound

Identifiers

PMID32042346
PMCPMC6993230
OpenAlexW3003607398

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.