Evidence map›Paper›PMID 32042319›Full record

ArticleTheranostics2020

The Effect of Cardiogenic Factors on Cardiac Mesenchymal Cell Anti-Fibrogenic Paracrine Signaling and Therapeutic Performance.

Justin S Heidel, Annalara G Fischer, Xian-Liang Tang, Ghazal Sadri, Wen-Jian Wu, Claudiu R Moisa, Heather Stowers, Neel Sandella, Marcin Wysoczynski, Shizuka Uchida and 1 more

Open access · goldAbstract read
In one paragraph

Article in Theranostics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Matricellular protein CCN1 promotes collagen alignment and scar integrity after myocardial infarction.Matrix biology : journal of the International Society for Matrix Biology · 2024
    Article
  3. Article
  4. Collagen type XIX regulates cardiac extracellular matrix structure and ventricular function.Matrix biology : journal of the International Society for Matrix Biology · 2022
    Article
  5. Article
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Justin S HeidelDiabetes and Obesity Center, Department of Medicine, University of Louisville, Louisville, KY, USA.
Annalara G FischerDiabetes and Obesity Center, Department of Medicine, University of Louisville, Louisville, KY, USA.
Xian-Liang TangInstitute of Molecular Cardiology, Department of Medicine, University of Louisville, Louisville, KY, USA.
Ghazal SadriDiabetes and Obesity Center, Department of Medicine, University of Louisville, Louisville, KY, USA.
Wen-Jian WuInstitute of Molecular Cardiology, Department of Medicine, University of Louisville, Louisville, KY, USA.
Claudiu R MoisaInstitute of Molecular Cardiology, Department of Medicine, University of Louisville, Louisville, KY, USA.
Heather StowersInstitute of Molecular Cardiology, Department of Medicine, University of Louisville, Louisville, KY, USA.
Neel SandellaDiabetes and Obesity Center, Department of Medicine, University of Louisville, Louisville, KY, USA.
Marcin WysoczynskiDiabetes and Obesity Center, Department of Medicine, University of Louisville, Louisville, KY, USA.
Shizuka UchidaDiabetes and Obesity Center, Department of Medicine, University of Louisville, Louisville, KY, USA.
Joseph B Moore IvDiabetes and Obesity Center, Department of Medicine, University of Louisville, Louisville, KY, USA.
University of Louisville · US

Funding

Tumor Necrosis Factor Modulation of CPCsP01HL078825 · NHLBI · UNIVERSITY OF LOUISVILLE · PI BOLLI, ROBERTO · 2005 to 2021
$37.6M
TBDP30GM127607 · NIGMS · UNIVERSITY OF LOUISVILLE · PI BHATNAGAR, ARUNI · 2018 to 2022
$6.3M
The Role of Cardiomyogenic Lineage Commitment in Cardiac Mesenchymal Cell-Mediated Extracellular Vesicle Signaling and Cardiac RepairR01HL141081 · NHLBI · UNIVERSITY OF LOUISVILLE · PI MOORE IV, JOSEPH B · 2018 to 2022
$1.9M
The role of bioactive lipids in CMC-induced myocardial repair.R01HL141191 · NHLBI · UNIVERSITY OF LOUISVILLE · PI WYSOCZYNSKI, MARCIN · 2019 to 2023
$1.9M
NHLBI NIH HHS P01 HL078825NHLBI NIH HHS R01 HL141081NHLBI NIH HHS R01 HL141191NIGMS NIH HHS P30 GM127607
6 · The paper itself

Abstract

Intrinsic cardiogenic factor expression, a proxy for cardiomyogenic lineage commitment, may be an important determinant of donor cell cardiac reparative capacity in cell therapy applications; however, whether and how this contributes to their salutary effects remain largely ambiguous.

Indexed as

AnimalsCardiomyopathiesCell- and Tissue-Based TherapyCell ProliferationCollagenCulture Media, ConditionedCytokinesDNA-Binding ProteinsFemaleFibroblastsMesenchymal Stem CellsMesenchymal Stem Cell TransplantationMyocardial InfarctionMyocardiumMyocytes, CardiacMyogenic Regulatory FactorsCollagenCulture Media, ConditionedCytokinesDNA-Binding ProteinsMyogenic Regulatory FactorsCardiac Mesenchymal CellsFibrosisMyocardial InfarctionParacrine SignalingTherapy

Identifiers

PMID32042319
PMCPMC6993223
OpenAlexW2997147329

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.