Evidence map›Paper›PMID 32042144›Full record

ReviewNature reviews. Neuroscience2020

Dentate gyrus circuits for encoding, retrieval and discrimination of episodic memories.

Thomas Hainmueller, Marlene Bartos

Abstract readReview
In one paragraph

Review in Nature reviews. Neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 273 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
273citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

273 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Spatially resolved mNature methods · 2026
    Article
  13. The role of GABANeuroscience and biobehavioral reviews · 2026
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

213 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Thomas HainmuellerInstitute for Physiology I, Systemic and Cellular Neurophysiology, Medical Faculty, University of Freiburg, Freiburg, Germany. Thomas.Hainmueller@physiologie.uni-freiburg.de.ORCID http://orcid.org/0000-0002-7824-5927
Marlene BartosInstitute for Physiology I, Systemic and Cellular Neurophysiology, Medical Faculty, University of Freiburg, Freiburg, Germany. Marlene.Bartos@physiologie.uni-freiburg.de.ORCID http://orcid.org/0000-0001-9741-1946

Funding

European Research Council 787450
6 · The paper itself

Abstract

The dentate gyrus (DG) has a key role in hippocampal memory formation. Intriguingly, DG lesions impair many, but not all, hippocampus-dependent mnemonic functions, indicating that the rest of the hippocampus (CA1-CA3) can operate autonomously under certain conditions. An extensive body of theoretical work has proposed how the architectural elements and various cell types of the DG may underlie its function in cognition. Recent studies recorded and manipulated the activity of different neuron types in the DG during memory tasks and have provided exciting new insights into the mechanisms of DG computational processes, particularly for the encoding, retrieval and discrimination of similar memories. Here, we review these DG-dependent mnemonic functions in light of the new findings and explore mechanistic links between the cellular and network properties of, and the computations performed by, the DG.

Indexed as

Memory, EpisodicAnimalsDentate GyrusDiscrimination LearningEntorhinal CortexHumansMemory ConsolidationMental RecallModels, NeurologicalNeurons

Identifiers

PMID32042144
PMCPMC7115869

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.