ArticleScientific reports2020
Effect of mild blast-induced TBI on dendritic architecture of the cortex and hippocampus in the mouse.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 42 citations in OpenAlex.
- Explosive shock wave exposure leads to age-accelerated motor and sensory decline inbioRxiv : the preprint server for biology · 2025Article
- Article
- Sex and Genotype Affect Mouse Hippocampal Gene Expression in Response to Blast-Induced Traumatic Brain Injury.Molecular neurobiology · 2025Article
- Assessment model of blast injury: A narrative review.iScience · 2025Review
- Animal Models of Traumatic Brain Injury and Their Relevance in Clinical Settings.CNS neuroscience & therapeutics · 2025Review
- Quantitative proteomic profiling in brain subregions of mice exposed to open-field low-intensity blast reveals position-dependent blast effects.Shock waves · 2024Article
- Knowledge and attitudes toward mild traumatic brain injury among patients and family members.Frontiers in public health · 2024Article
- Lifestyle strategies to promote proteostasis and reduce the risk of Alzheimer's disease and other proteinopathies.Ageing research reviews · 2024Review
- Single-nucleus transcriptomic mapping of blast-induced traumatic brain injury in mice hippocampus.Scientific data · 2023Article
- Mechanisms of mechanical load transfer through brain tissue.Scientific reports · 2023Article
- Behavioral changes and dendritic remodeling of hippocampal neurons in adolescent alcohol-treated rats.Advances in drug and alcohol research · 2023Article
- Bedside to bench: the outlook for psychedelic research.Frontiers in pharmacology · 2023Review
- Sidestream Smoke Affects Dendritic Complexity and Astrocytes After Model Mild Closed Head Traumatic Brain Injury.Cellular and molecular neurobiology · 2022Article
- Limbic Responses Following Shock Wave Exposure in Male and Female Mice.Frontiers in behavioral neuroscience · 2022Article
- Recent Developments in Mouse Trauma Research Models: A Mini-Review.Frontiers in physiology · 2022Review
- Volume reduction without neuronal loss in the primate pulvinar complex following striate cortex lesions.Brain structure & function · 2021Article
- Teasing apart trauma: neural oscillations differentiate individual cases of mild traumatic brain injury from post-traumatic stress disorder even when symptoms overlap.Translational psychiatry · 2021Article
- Dendritic arbor complexity and spine density changes after repetitive mild traumatic brain injury and neuroprotective treatments.Brain research · 2020Article
- Low brain endocannabinoids associated with persistent non-goal directed nighttime hyperactivity after traumatic brain injury in mice.Scientific reports · 2020Article
- Mild Traumatic Brain Injury Induces Transient, Sequential Increases in Proliferation, Neuroblasts/Immature Neurons, and Cell Survival: A Time Course Study in the Male Mouse Dentate Gyrus.Frontiers in neuroscience · 2020Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
Abstract
Traumatic brain injury (TBI) has been designated as a signature injury of modern military conflicts. Blast trauma, in particular, has come to make up a significant portion of the TBIs which are sustained in warzones. Though most TBIs are mild, even mild TBI can induce long term effects, including cognitive and memory deficits. In our study, we utilized a mouse model of mild blast-related TBI (bTBI) to investigate TBI-induced changes within the cortex and hippocampus. We performed rapid Golgi staining on the layer IV and V pyramidal neurons of the parietal cortex and the CA1 basilar tree of the hippocampus and quantified dendritic branching and distribution. We found decreased dendritic branching within both the cortex and hippocampus in injured mice. Within parietal cortex, this decreased branching was most evident within the middle region, while outer and inner regions resembled that of control mice. This study provides important knowledge in the study of how the shockwave associated with a blast explosion impacts different brain regions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.