Evidence map›Paper›PMID 32041900›Full record

ArticleDiabetes care2020

Lactation Duration and Long-term Risk for Incident Type 2 Diabetes in Women With a History of Gestational Diabetes Mellitus.

Sylvia H Ley, Jorge E Chavarro, Mengying Li, Wei Bao, Stefanie N Hinkle, Pandora L Wander, Janet Rich-Edwards, Sjurdur Olsen, Allan Vaag, Peter Damm and 4 more

Abstract read
In one paragraph

Article in Diabetes care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Improving Breastfeeding by Empowering Mothers in Vietnam: A Randomised Controlled Trial of a Mobile App.International journal of environmental research and public health · 2020
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  16. Breastfeeding and Maternal and Child Cardiometabolic Outcomes 10-14 Years after Delivery.Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Sylvia H LeyDepartment of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA zhangcu@mail.nih.gov sley@tulane.edu.ORCID 0000-0003-0084-2630
Jorge E ChavarroDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA.ORCID 0000-0002-4436-9630
Mengying LiDivision of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD.
Wei BaoDepartment of Epidemiology, University of Iowa, Iowa City, IA.ORCID 0000-0002-7301-5786
Stefanie N HinkleDivision of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD.
Pandora L WanderDepartment of Medicine, University of Washington, Seattle, WA.
Janet Rich-EdwardsDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA.
Sjurdur OlsenDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA.
Allan VaagSteno Diabetes Center Copenhagen, Copenhagen, Denmark.
Peter DammDepartment of Obstetrics, Center for Pregnant Women with Diabetes, Rigshospitalet, and Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
Louise G GrunnetDepartment of Endocrinology, Diabetes and Bone-Metabolic Research Unit, Rigshospitalet, Copenhagen, Denmark.
James L MillsDivision of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD.
Frank B HuDepartment of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA.
Cuilin ZhangDivision of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD zhangcu@mail.nih.gov sley@tulane.edu.ORCID 0000-0002-8014-2708

Funding

Risk Factors for Breast Cancer in Younger NursesR01CA050385 · NCI · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI ELIASSEN, A. HEATHER, WILLETT, WALTER C. · 1989 to 2019
$32.3M
Tulane COBRE in Cardiometabolic Diseases Clinical Research CoreP20GM109036 · NIGMS · TULANE UNIVERSITY OF LOUISIANA · PI Ning Liu · 2016 to 2026
$25.3M
Transgenic CoreP30DK046200 · NIDDK · TUFTS MEDICAL CENTER · PI CORKEY, BARBARA E. · 1992 to 2021
$25.0M
Life Course Cancer Epidemiology Cohort in WomenU01CA176726 · NCI · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI ELIASSEN, A. HEATHER, WILLETT, WALTER C. · 2018 to 2025
$22.4M
Integrating lifecourse approaches, biologic and digital phenotypes in support of heart and lung disease epidemiologic researchU01HL145386 · NHLBI · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI CHAVARRO, JORGE EDUARDO, MANSON, JOANN ELISABETH · 2019 to 2025
$17.8M
Premonopausal Hormone Levels and Risk of Breast CancerR01CA067262 · NCI · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI HANKINSON, SUSAN E · 2002 to 2011
$11.9M
Diabetes & Women's Health Study: long term health implications of GDMZIAHD008916 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI YEUNG, EDWINA · 2011 to 2022
$3.3M
Circulating plasma metabolites, diet, and risk of type 2 diabetesR01DK112940 · NIDDK · BRIGHAM AND WOMEN'S HOSPITAL · PI HU, FRANK B, MORA, SAMIA · 2018 to 2021
$2.9M
NCI NIH HHS R01 CA050385NCI NIH HHS R01 CA067262NCI NIH HHS U01 CA176726NHLBI NIH HHS U01 HL145386NICHD NIH HHS HHSN275201000020CNIDDK NIH HHS P30 DK046200NIDDK NIH HHS R01 DK112940NIGMS NIH HHS P20 GM109036
6 · The paper itself

Abstract

objectiveWe examined the association of lactation duration with incident type 2 diabetes among women with a history of gestational diabetes mellitus (GDM). RESEARCH DESIGN AND

methodsWe monitored 4,372 women with a history of GDM participating in the Nurses' Health Study II for incident type 2 diabetes over 25 years up to 2017. Lactation history was obtained through follow-up questionnaires to calculate lactation duration. Follow-up blood samples were collected from a subset of these women at median age of 58 years through the Diabetes & Women's Health Study.

resultsWe documented 873 incident cases of type 2 diabetes during 87,411 person-years of follow-up. Longer duration of lactation was associated with lower risk of type 2 diabetes for both total lactation (hazard ratio 1.05 [95% CI 0.83-1.34] for up to 6 months, 0.91 [0.72-1.16] for 6-12 months, 0.85 [0.67-1.06] for 12-24 months, and 0.73 [0.57-0.93] for >24 months, compared with 0 months;

conclusionsLonger duration of lactation is associated with a lower risk of type 2 diabetes and a favorable glucose metabolic biomarker profile among women with a history of GDM. The underlying mechanisms and impact on diabetes complications, morbidity, and mortality remain to be determined.

Indexed as

AdultBreast FeedingDiabetes, GestationalDiabetes Mellitus, Type 2ExerciseFemaleHumansIncidenceLactationMiddle AgedParityPregnancyRisk FactorsSurveys and QuestionnairesTime Factors

Identifiers

PMID32041900
PMCPMC7085808

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.